Sort   by:  
 Page size 
TranscriptomicsU2AF1 mutations alter splice site recognition in hematological malignancies
Whole-exome sequencing studies have identified common mutations affecting genes encoding components of the RNA splicing machinery in hematological malignancies. Here, we sought to determine how mutations affecting the 3' splice site recognition factor U2AF1 altered its normal role in RNA splicing. W...
ORGANISM(S): Homo sapiens 
2014-09-23 | E-GEOD-58871 | biostudies-arrayexpress
TranscriptomicsIsoform-specific depletion of U2AF1
RNA-Seq data of U2AF1 isoform depletion experiments.
ORGANISM(S): Homo sapiens 
2015-03-16 | E-MTAB-2682 | biostudies-arrayexpress
TranscriptomicsIdentification of differentially spliced genes by wild type or S34F mutation of U2AF1
Identification of differentially spliced genes by wild type or S34F mutation of U2AF1 Examination of effects on splicing events by overexpressing wipdtype or S34F mutation of two U2AF1 isoforms in A549 cells. All experimental conditions are performed in duplicate.
ORGANISM(S): Homo sapiens 
2015-11-01 | E-GEOD-66553 | biostudies-arrayexpress
GenomicsIsoform-specific depletion of U2AF1
Isoform-specific depletion of U2AF1
PRJEB6651 | ENA
GenomicsU2AF1-S34F and U2AF1-Q157R induce distinct RNA splicing and hematopoietic phenotypes in vivo
U2AF1-S34F and U2AF1-Q157R induce distinct RNA splicing and hematopoietic phenotypes in vivo
PRJNA1186736 | ENA
GenomicsEffect of U2AF1-S34F mutation in mouse neutrophils
Effect of U2AF1-S34F mutation in mouse neutrophils
PRJNA862495 | ENA
GenomicsU2AF1 mutations confer resistance to chemotherapy in AML
U2AF1 mutations confer resistance to chemotherapy in AML
PRJNA1078301 | ENA
GenomicsFunctional Significance of U2AF1 S34F Mutation in Lung Adenocarcinomas
Functional Significance of U2AF1 S34F Mutation in Lung Adenocarcinomas
PRJNA510433 | ENA
TranscriptomicsRNA-seq of LSK isolated from U2af1 mutant, Tet2 mutant and U2af1/Tet2 double mutant against wild-type controls.
To investigate the transcriptome of hematopoietic stem and progenitor cells (Lin-Sca-1+c-kit+) carrying alterations in splicing factors and/or epigenetic regulators related with the pathogenesis of myelodysplastic syndromes.
ORGANISM(S): Mus musculus 
2021-07-14 | E-MTAB-10486 | biostudies-arrayexpress
GenomicsU2AF1 mutations rescue deleterious exon skipping induced by KRAS mutations
U2AF1 mutations rescue deleterious exon skipping induced by KRAS mutations
PRJNA1456563 | ENA
Sort   by:  
 Page size