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TranscriptomicsHigh temporal resolution profiling of U2OS fibroblasts
High-temporal resolution profiling was performed on U2OS fibroblasts to detect rhythmic transcripts Keywords: time course Samples were collected every hour for 48 hours from dexamethasone-synchronized U2OS cells. Cells synchronized with dexamethasone for 24 hours, and harvested from the 24th to 71...
ORGANISM(S): Homo sapiens 
2008-12-14 | E-GEOD-13949 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human U2OS cells expressing estrogen receptor alpha and beta heterodimers and treated with 17beta-estradiol or 4OH-tamoxifen
U2OS-ERa, U2OS-ERb, and U2OS-ERab cells treated with 4HT or E2
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-2292 | biostudies-arrayexpress
TranscriptomicsIdentification of cell cycle-regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors
We identified the cell cycle-regulated mRNA transcripts genome-wide in the osteosarcoma derived U2OS cell line. This resulted in 2,140 transcripts mapping to 1,871 unique cell cycle-regulated genes that show periodic oscillations across multiple synchronous cell cycles. We identified genomic loci ...
ORGANISM(S): Homo sapiens 
2013-10-11 | E-GEOD-50988 | biostudies-arrayexpress
GenomicsHomo sapiens strain:U2OS
H4K20 methylation in cell cycle of U2OS
PRJNA225006 | ENA
TranscriptomicsGenome-wide profiling of H3K27ac, H3K4me1, H3K27me3 and H3K9me3 (ChIP-seq) in U2OS-GR and U2OS-AR cells
We performed ChIP-seq targeting the H3K27ac, H3K4me1, H3K27me3 and H3K9me3 in the U2OS-GR and U2OS-AR cell lines. The cell lines are derived from U2OS ATTC:HTB-96 and stably transfected with an expression construct for either rat GR or human AR, respectively. The U2OS-GR cells were treated with dexa...
ORGANISM(S): Homo sapiens 
2021-03-09 | E-MTAB-9617 | biostudies-arrayexpress
GenomicsHistone H3K18ac ChIP-seq in U2OS cells
Chromatin immuno-precipitation using anti-H3K18ac antibodies in U2OS cells.
ORGANISM(S): Homo sapiens 
2016-04-27 | E-MTAB-3695 | biostudies-arrayexpress
TranscriptomicsGlucocorticoid and androgen receptor profiling (ChIP-seq) in U2OS-GR and U2OS-AR cells upon hormone treatment
We performed ChIP-seq targeting the glucocorticoid receptor (GR) in the U2OS-GR cell line and the androgen receptor (AR) in the U2OS-AR cell line. The cell lines are derived from U2OS ATTC:HTB-96 and stably transfected with an expression construct for either rat GR or human AR, respectively. The U2O...
ORGANISM(S): Homo sapiens 
2021-03-09 | E-MTAB-9616 | biostudies-arrayexpress
GenomicsSUMO2 ChIP-seq in U2OS cells
Chromatin immuno-precipitation using SUMO2 (Life Technologies) antibody in U2OS cell line.
ORGANISM(S): Homo sapiens 
2015-08-07 | E-MTAB-3084 | biostudies-arrayexpress
TranscriptomicsGene expression of osteosarcoma cell (U2OS, MG63) lines relative to normal human osteoblasts (HOB)
Gain or loss of genes and deregulation of gene expression can result in cumulative and progressive disruptions of normal cellular functions. Cancer-specific changes in gene expression play an essential role in cancer occurrence, and ultimately lead to cancer-related self-sufficiency in growth signal...
ORGANISM(S): Homo sapiens 
2009-05-01 | E-GEOD-11414 | biostudies-arrayexpress
GenomicsHomo sapiens strain:U2OS
DDX17 CLIP-seq in U2OS cells with and without Rift Valley Fever Virus infection.
PRJNA244543 | ENA
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