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TranscriptomicsProfile of gene expression in U87-MG xenografts expressing control vector (V0), the ubiquitin ligase KPC1 or the p50 subunit of the NF-kB transcription factor, using RNASeq analysis of transcripts mapped independently to the human and murine genomes
Purpose: We identified KPC1 as the ubiquitin ligase that binds to the p105 precursor of NF-kB, ubiquitinates it and mediates its proteasomal processing to generate the p50 active subunit of the transcription factor. Using U87-MG human glioblastoma xenografts, we observed that overexpression of KPC1 ...
ORGANISM(S): Homo sapiens 
2015-04-09 | E-GEOD-60530 | biostudies-arrayexpress
GenomicsHomo sapiens strain:U87 MG
Global Gene Expression Profiling Reveals Curcumin-Induced Molecular Mechanisms in U87 MG Glioblastoma Cells
PRJNA1243709 | ENA
TranscriptomicsmiRNA analysis of HBMVECs exposed or unexposed to U87 glioma cells
A key step in angiogenesis is the upregulation of growth factor receptors on endothelial cells. Here we demonstrate that a small regulatory microRNA, miR-296 has a major role in this process. Glioma cells and angiogenic growth factors elevate the level of miR-296 in primary human brain microvascular...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-13091 | biostudies-arrayexpress
TranscriptomicsHypoxia-responsive gene expression profile of U87 MG glioblastoma cells and their exosomes.
How cancer cells adapt to hypoxia during tumor development remains an important question. The hypothesis tested in the present study was that tumor cell-derived exosome vesicles (also known as microvesicles or extracellular vesicles) are mediators of hypoxia-dependent intercellular signaling in gli...
ORGANISM(S): Homo sapiens 
2013-03-20 | E-GEOD-45301 | biostudies-arrayexpress
TranscriptomicsHuman Mesenchymal Stem Cells Exploit the Immune Response Mediating Chemokines to Impact the Phenotype of Glioblastoma
Four human mesenchymal stem cells (hMSC) clones (MSC-1, MSC-2, MSC-3, MSC-4) and three different glioblastoma multiformae (GBM) cell lines (U87-MG, U251, U373) were used to study their mutual paracrine interactions in the indirect co-cultures compared to their monocultures, which were grown under th...
ORGANISM(S): Homo sapiens 
2011-12-20 | E-GEOD-26283 | biostudies-arrayexpress
no omics definedTranscription profiling of camptothecin treatment time series performed on human U87 glioma cells
Time-series analysis of camptothecin effects on U87 glioma cells
ORGANISM(S): Homo sapiens 
2006-09-30 | E-MEXP-741 | biostudies-arrayexpress
GenomicsDifferential m6A methylation between parental and temozolomide resistant U87 MG cells
Differential m6A methylation between parental and temozolomide resistant U87 MG cells
PRJNA1311119 | ENA
GenomicsGenome-wide binding of RNF2 in control and GPR17 knock-down U87-MG cells
Genome-wide binding of RNF2 in control and GPR17 knock-down U87-MG cells
PRJNA728458 | ENA
TranscriptomicsExpression Profiling: Guanylate Cyclase Soluble Subunit Beta-3 (GUCY1B3) overexpression U87 MG cells
Total RNA were extracted from Guanylate Cyclase Soluble Subunit Beta-3 (GUCY1B3) overexpression U87 MG stable cell lines and U87 MG cells. Three RNA samples of each of the two cell lines were used for microarray analysis to compare gene expression profile
ORGANISM(S): Homo sapiens 
2016-06-15 | GSE83344 | GEO
ProteomicsIdentification of human NCOA7-AS binding partners
The interferon inducible isoform of human NCOA7 (NCOA7-AS, for Alternative Start) is a TLDc protein that has been shown to be antiviral against influenza A virus and to interact with cytoplasmic subunits of the V-ATPase. Upon its ectopic expression, there is a decrease in endolysosomal pH that seems...
ORGANISM(S): Homo sapiens (Human) 
2026-08-27 | PXD080054 | Pride
Human U87-mg cells Ncoa7-as isg 
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