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ProteomicsAuto-sumoylation of the Ubc9 E2 SUMO-conjugating Enzyme Extends Cellular Lifespan
Calorie restriction (CR) provides anti-aging benefits through diverse processes, such as reduced metabolism and growth and increased mitochondrial activity. Although controversy still exists regarding CR-mediated lifespan effects, many researchers are seeking interventions that mimic the effects of ...
ORGANISM(S): Saccharomyces cerevisiae Saccharomyces cerevisiae (Baker's yeast) 
2025-01-15 | PXD048944 | Pride
Sumo Ubc9. lifespan 
ProteomicsAuto-sumoylation of the Ubc9 E2 SUMO-conjugating Enzyme Extends Cellular Lifespan
Calorie restriction (CR) provides anti-aging benefits through diverse processes, such as reduced metabolism and growth and increased mitochondrial activity. Although controversy still exists regarding CR-mediated lifespan effects, many researchers are seeking interventions that mimic the effects of ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-01-15 | PXD049427 | Pride
Lc ms/ms Sumo  ubc9  lifespan  energy metabolism  calorie restriction 
GenomicsAuto-sumoylation of the Ubc9 E2 SUMO-conjugating Enzyme Extends Cellular Lifespan
Auto-sumoylation of the Ubc9 E2 SUMO-conjugating Enzyme Extends Cellular Lifespan
PRJNA1063721 | ENA
GenomicsAuto-sumoylation of the Ubc9 E2 SUMO-conjugating Enzyme Extends Cellular Lifespan (RNA-Seq)
Auto-sumoylation of the Ubc9 E2 SUMO-conjugating Enzyme Extends Cellular Lifespan (RNA-Seq)
PRJNA1072738 | ENA
GenomicsAuto-sumoylation of the Ubc9 E2 SUMO-conjugating Enzyme Extends Cellular Lifespan
Yeast has proven to be a useful model system for aging studies, including CR effects. We report here that yeast adapted through in vitro evolution to the severe cellular stress caused by loss of the Ulp2 SUMO-specific protease exhibit both enhanced growth rates and replicative lifespan, and they hav...
ORGANISM(S): Saccharomyces cerevisiae 
2024-04-17 | GSE253055 | GEO
TranscriptomicsAuto-sumoylation of the Ubc9 E2 SUMO-conjugating Enzyme Extends Cellular Lifespan (RNA-Seq)
Yeast has proven to be a useful model system for aging studies, including CR effects. We report here that yeast adapted through in vitro evolution to the severe cellular stress caused by loss of the Ulp2 SUMO-specific protease exhibit both enhanced growth rates and replicative lifespan, and they hav...
ORGANISM(S): Saccharomyces cerevisiae 
2024-04-17 | GSE254981 | GEO
GenomicsUbc9 auto-sumoylation-associated changes in the genome-wide pattern of SUMO enrichment.
Calorie restriction (CR) provides anti-aging benefits through diverse processes, such as reduced metabolism and growth and increased mitochondrial activity. Although controversy still exists regarding CR-mediated lifespan effects, many researchers are seeking interventions that mimic the effects of ...
ORGANISM(S): Saccharomyces cerevisiae 
2025-01-15 | GSE278286 | GEO
GenomicsUbc9 auto-sumoylation-associated changes in the genome-wide pattern of SUMO enrichment.
Ubc9 auto-sumoylation-associated changes in the genome-wide pattern of SUMO enrichment.
PRJNA1166211 | ENA
GenomicsGene expression changes in ovaries of oocyte-specific conditional knockout of Ubc9 in juvenile mice
Gene expression changes in ovaries of oocyte-specific conditional knockout of Ubc9 in juvenile mice
PRJNA550147 | ENA
TranscriptomicsGene expression changes in ovaries of oocyte-specific conditional knockout of Ubc9 in juvenile mice
The reproductive lifespan in mammals is largely determined by the abundance and quality of oocytes residing within the primoridial ovarian follicular pool. Critical oocyte-expressed genes driving ovarian function have been identified, buta role for post-translational modifications, such as SUMOylati...
ORGANISM(S): Mus musculus 
2019-11-15 | GSE133179 | GEO
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