Ubiquitin-specific protease 2

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Unknown (196)
Transcriptomics (173)
Proteomics (153)
Genomics (46)
Metabolomics (4)
Other (2)

Organisms

Allexis (120)
Arabidopsis thaliana (120)
Entamoeba histolytica HM-1:IMSS-A (120)
Escherichia coli (120)
Homo sapiens (120)
Listeria monocytogenes (120)
Medicago truncatula (120)
Meleagris gallopavo (120)
Methylohalobius crimeensis 10Ki (120)
Homo sapiens (79)
Mus musculus (72)
Saccharomyces cerevisiae (11)
Drosophila melanogaster (11)
Rattus norvegicus (9)
Arabidopsis thaliana (6)
Schizosaccharomyces pombe (3)
Caenorhabditis elegans (3)
Cryptococcus neoformans (3)
Sus scrofa (3)
Saccharomyces cerevisiae SK1 (2)
Gallus gallus (2)
Citrus reticulata (2)
Mus musculus castaneus (1)
Tetrahymena thermophila (1)
Macaca mulatta (1)
Entamoeba histolytica (1)
Apis mellifera (1)
Oncorhynchus mykiss (1)
Mycobacterium tuberculosis H37Rv (1)
Danio rerio (1)

Organisms

Mus musculus (6)
Homo sapiens (6)
Arabidopsis thaliana (3)
Drosophila melanogaster (1)
Saccharomyces cerevisiae (1)

Repository

biostudies-arrayexpress (185)
pride (120)
ENA (17)
geo (16)
MassIVE (16)
iProX (11)
MetaboLights (4)
EGA (3)
GPMDB (2)
jPOST (2)
PAXDB (2)

Tissue

Cell culture (43)
Epithelial cell (14)
Brain (9)
Permanent cell line cell (9)
Bone marrow (4)
Kidney (4)
Lung (4)
Blood (3)
Whole body (3)
B cell (2)
Blood cell (2)
Embryonic stem cell (2)
Epithelial cell of cervix (2)
HeLa cell (2)
Heart (2)
Leaf (2)
Macrophage (2)
Skeletal muscle (2)
Spleen (2)
T cell (2)
Cell suspension culture (1)
Colon (1)
Colonic epithelium (1)
Dendritic cell (1)
Diaphragm (1)
Dorsal root ganglion (1)
Early embryonic cell (1)
Egg (1)
Embryo (1)
HEK-293 cell (1)

Disease

Cervix carcinoma (4)
Breast cancer (3)
Normal (2)
Not Available (2)
Colon cancer (2)
Psoriasis vulgaris (1)
Liver cancer (1)
Multiple myeloma (1)
Acute leukemia (1)
Adult hepatocellular carcinoma (1)
Amyotrophic lateral sclerosis (1)
Anemia (1)
Arthrogryposis multiplex congenita-1 (1)
Cervical cancer (1)
Chronic lymphocytic leukemia (1)
Diaphragm disease (1)
Fetal akinesia deformation sequence syndrome (1)
Hematopoietic system disease (1)
Herpes simplex (1)
Hypochromic anemia (1)
Kidney cancer (1)
Lung cancer (1)
Malaria (1)
Melanoma (1)
Neuroblastoma (1)
Neurodegenerative disease (1)
Neurodevelopmental delay (1)
Pancreatic carcinoma (1)
Parasitic infectious disease (1)
Parkinson's disease (1)

Technology Type

Mass Spectrometry (120)
Shotgun proteomics (51)
Affinity purification coupled with mass spectrometry proteomics (32)
Bottom-up proteomics (27)
Data-dependent acquisition (17)
Data-independent acquisition (11)
Gel-based experiment (5)
SRM/MRM (5)
Chemical cross-linking coupled with mass spectrometry proteomics (3)
Mass spectrometry assay (2)
Mass spectrometry (2)
Affinity proteomics (2)
HDMSE (2)
SWATH MS (2)
Top-down proteomics (2)
DiaPASEF (1)
MSE (1)

Instrument Platform

Illumina NovaSeq 6000 (13)
NextSeq 550 (7)
Q Exactive (5)
NextSeq 500 (4)
LTQ Orbitrap Velos (4)
Sony SH800 (2)
None (2)
Illumina HiSeq 2500 (2)
Illumina HiSeq 2000 (2)
Instrument (2)
Dionex instrument model (2)
Q Exactive HF (2)
Q Exactive Plus (2)
Agilent TapeStation (1)
Eppendorf EpMotion 5073m pipetting robot (1)
IEO HPC (1)
Element AVITI (1)
Qubit instrument, DNA HS kit (1)
High Sensitivity DNA kit (1)
BioRad SureCell (1)
Unspecified (1)
Illumina Genome Analyzer IIx (1)
DNA Microarray Scanner BA [Agilent Technologies] (1)
NA (1)
Illumina (1)
NextSeq 2000 (1)
Illumina MiSeq (1)
Illumina HiSeq 1500 (1)
Illumina HiSeq 4000 (1)
LTQ (Thermo Scientific instrument model) (1)

Publication Date

2025 (52)
2013 (30)
2023 (29)
2014 (29)
2015 (24)
2026 (22)
2012 (19)
2024 (18)
2011 (17)
2016 (13)
2021 (13)
2022 (12)
2018 (11)
2008 (11)
2019 (10)
2010 (10)
2020 (8)
2007 (6)
2017 (5)
2009 (4)
2005 (1)
2004 (1)

UNIPROT ID/AC

5833.MAL13P1.267 (2)
5833.MAL13P1.269 (2)
5833.MAL13P1.325 (2)
5833.MAL13P1.334 (2)
5833.MAL7P1.78 (2)
5833.MAL8P1.208 (2)
5833.MAL8P1.320 (2)
5833.PF11_0033 (2)
5833.PF11_0263 (2)
5833.PF11_0512 (2)
5833.PF13_0305 (2)
5833.PF13_0321 (2)
5833.PF14_0001 (2)
5833.PF14_0009 (2)
5833.PF14_0173 (2)
5833.PF14_0734 (2)
5833.PF14_0751 (2)
5833.PF14_0756 (2)
5833.PF14_0759 (2)
5833.PFA0105w (2)
5833.PFA0120c (2)
5833.PFA0705c (2)
5833.PFB0050c (2)
5833.PFB0280w (2)
5833.PFB0925w (2)
5833.PFB0946c (2)
5833.PFC1011c (2)
5833.PFC1075w (2)
5833.PFD0075w (2)
5833.PFD0100c (2)

CHEBI ID

CHEBI:136091 (2)
CHEBI:136137 (2)
CHEBI:136127 (2)
CHEBI:136135 (2)
CHEBI:134639 (2)
CHEBI:134541 (2)
CHEBI:136281 (2)
CHEBI:136189 (2)
CHEBI:136133 (2)
CHEBI:136149 (2)
CHEBI:136081 (2)
CHEBI:136086 (2)
CHEBI:90470 (2)
CHEBI:136088 (2)
CHEBI:136071 (2)
CHEBI:90433 (2)
CHEBI:134592 (2)
CHEBI:72961 (2)
CHEBI:75062 (2)
CHEBI:73000 (2)
CHEBI:133672 (2)
CHEBI:107726 (2)
CHEBI:85593 (2)
CHEBI:134598 (2)
CHEBI:83358 (2)
CHEBI:72999 (2)
CHEBI:16566 (2)
CHEBI:16393 (2)
CHEBI:136242 (1)
CHEBI:73223 (1)

Metabolite Name

PG(18:1/0:0) (1)
PE(P-16:0/22:1) (1)
PE(O-18:1/0:0) (1)
PE(18:1/22:0) (1)
PE(18:0/19:1) (1)
PE(16:1/18:0) (1)
PE(17:1/18:0) (1)
GM3(38:2) (1)
GM3(36:1) (1)
GM3(34:1) (1)
CL(20:2/16:1/18:1/18:3) (1)
CL(18:3/18:1/18:3/20:3) (1)
CL(18:2/18:2/18:2/18:3) (1)
PE(24:0/18:1) (1)
Uridine 5'-triphosphate (UTP) (1)
Uridine 5'-diphosphate (UDP) (1)
Galactosamine (1)
Tricosanoyl sphingomyelin (d18:1/23:0)* (1)
Stearoyl-docosahexaenoyl-glycerol (18:0/22:6) [2]* (1)
Stearoyl-arachidonoyl-glycerol (18:0/20:4) [2]* (1)
Stearoyl-arachidonoyl-glycerol (18:0/20:4) [1]* (1)
Sphingomyelin (d18:2/16:0, d18:1/16:1)* (1)
Sphingomyelin (d18:1/19:0, d19:1/18:0)* (1)
Sphingomyelin (d18:0/18:0, d19:0/17:0)* (1)
S-adenosylmethionine (SAM) (1)
Xylulose (1)
Pentadecanoylcarnitine (C15)* (1)
Palmitoyl-palmitoyl-glycerol (16:0/16:0) [2]* (1)
Palmitoyl-oleoyl-glycerol (16:0/18:1) [2]* (1)
Palmitoyl-myristoyl-glycerol (16:0/14:0) [2] (1)

First Public Date

2023 (6)
2024 (2)
2022 (2)
2020 (2)
2026 (1)
2018 (1)
2017 (1)
2015 (1)
2014 (1)

Study type

Transcription profiling by array (83)
RNA-seq of coding RNA (30)
ChIP-seq (22)
RNA-seq of coding RNA from single cells (8)
Other (7)
Unknown experiment type (6)
ChIP-chip by array (6)
Comparative genomic hybridization by array (6)
ChIP-chip by tiling array (3)
Genotyping by array (2)
RIP-seq (2)
MicroRNA profiling by array (2)
DNA-seq (2)
Proteomic profiling by array (2)
Transcription profiling by SAGE (1)
Cell line - One-color microarray (1)
Methylation profiling by array (1)
RNA-seq of total RNA (1)

Release Date

2025 (36)
2013 (35)
2015 (34)
2014 (30)
2022 (29)
2012 (26)
2023 (25)
2011 (23)
2016 (18)
2024 (17)
2020 (16)
2021 (15)
2010 (12)
2008 (11)
2026 (9)
2018 (9)
2017 (9)
2007 (8)
2019 (7)
2009 (5)
2005 (3)
2006 (3)
2004 (1)

Lab affiliation

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA (7)
Institute of Molecular Biology (IMB), Mainz, Germany (4)
CECAD, University of Cologne (2)
COI-NDM (University of Oxford) (2)
Department of Pathology and Cell Biology and Institute for Cancer Genetics Herbert Irving Comprehensive Cancer Vagelos College of Physicians & Surgeons Columbia University (2)
Erasmus MC (2)
Finley and Gygi lab Cell Biology Department Harvard Medical School US (2)
Institute of Biochemistry II, Faculty of Medicine, Goethe University, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany (2)
Institute of Biochemistry II, University Hospital, Goethe University, Frankfurt, Germany (2)
Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, Collaborative Innovation Center of Hematology, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200000, China (2)
The University of Melbourne (2)
Acting Head of Proteomics (1)
Additional Professor, Department of Medical Oncology (Lab.), Dr B.R.A.I.R.C.H., AIIMS, New Delhi (1)
Army Medical University (Third Military Medical University) (1)
Bioanalytical Mass Spectrometry, Max Planck Institute for Multidisciplinary Sciences, Goettingen, Germany (1)
CABIMER (1)
CAMS Key Laboratory of Translational Research on Lung Cancer, State Key Laboratory of Molecular Oncology, Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College (1)
CCB, LUMC, Netherlands (1)
COI-NDM Univesity of Oxford (1)
CRUK/MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford OX3 7DQ, UK (1)
Cambridge Institute for Medical Research, University of Cambridge (1)
Cell and Chemical Biology Leiden University Medical Center The Netherlands (1)
Center for Proteomics & Metabolomics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA (1)
Center for Synthetic Microbiology & Department of Chemistry, Marburg University,Hans-Meerwein-Straße 4, 35043 Marburg, Germany (1)
Department of Biochemistry, Biophysics and General Pathology, University of Campania “Luigi Vanvitelli”, Vico L. De Crecchio 7, 80138 Napoli, IT (1)
Department of Biological Sciences, Vanderbilt University (1)
Department of Biology - New York University Center for Genomics and Systems Biology New York, NY , USA (1)
Department of Biology, Duke University, USA (1)
Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, China (1)
Department of Biomedical Sciences, Seoul National University Graduate School, Seoul 03080, Korea. (1)

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Urinary Ubiquitin-Specific Protease 2 (USP2) as a Diagnostic Biomarker for Chronic Kidney Disease: An Integrated Multi-Omics and Network Analysis

Urinary USP2 is elevated in chronic kidney disease and shows strong diagnostic performance. Integrated metabolomics and proteomics analyses identified cortisol and prostaglandin A3 as candidate mediators and linked USP2 to lipid metabolism and ferroptosis-related pathways.

2026-05-05 | MTBLS14426 | MetaboLights

Proximity-dependent biotinylation reveals an interaction between ubiquitin-specific peptidase 46 and centrosome-related proteins

To characterize the protein interaction network of USP46, BioID analysis was conducted on a knock-in cell line that expresses USP46 and biotin ligase fusion protein stably.

ORGANISM(S): Mus Musculus (mouse)

2025-03-25 | PXD053674 | JPOST Repository

Ubiquitin-specific Protease 11 (USP11) Deubiquitinates Hybrid Small Ubiquitin-like Modifier (SUMO)-Ubiquitin Chains to Counteract RING Finger Protein 4 (RNF4).

Not available

S-EPMC4477612 | biostudies-literature

Macrophage ubiquitin-specific protease 2 modifies insulin sensitivity in obese mice.

Not available

S-EPMC5614627 | biostudies-literature

Ubiquitin-specific protease USP34 controls osteogenic differentiation and bone formation by regulating BMP2 signaling

PRJNA476060 | ENA

Peroxisomal localization and circadian regulation of ubiquitin-specific protease 2.

Not available

S-EPMC3487853 | biostudies-literature

RNA-Sequencing of USP15 conditional knock-out mice injected with kainate - dataset 2

Transcriptome studies of brain resections from mesial temporal lobe epilepsy (mTLE) patients revealed a dysregulation of transforming growth factor (TGF)-β, interferon (IFN)-α/β and nuclear factor erythroid 2-related factor 2 (NRF2) pathways among other neuroinflammatory mechanisms. Since ubiquitin-...

ORGANISM(S): Mus musculus

2023-10-12 | E-MTAB-12634 | biostudies-arrayexpress

Structure of ubiquitin-fold modifier 1-specific protease UfSP2.

Not available

S-EPMC3060479 | biostudies-literature

Overexpression of Ubiquitin-Specific Protease 2 (USP2) in the Heart Suppressed Pressure Overload-Induced Cardiac Remodeling.

Not available

S-EPMC7492881 | biostudies-literature

Identification of ubiquitin-specific protease 9X (USP9X) as a deubiquitinase acting on ubiquitin-peroxin 5 (PEX5) thioester conjugate.

Not available

S-EPMC3339989 | biostudies-literature