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TranscriptomicsGenome level identification of direct Ubx targets from third-instar imaginal discs
Hox proteins are transcription factors and key regulators of segmental identity along the anterior posterior axis across all bilateral animals. Despite decades of research, mechanism by which Hox proteins select their targets and specify segmental identity remains elusive. To address this question w...
ORGANISM(S): Drosophila melanogaster 
2011-12-22 | E-GEOD-28778 | biostudies-arrayexpress
TranscriptomicsDrosophila expression data from larval, prepupal and pupal wings to identify targets of Hox protein Ultrabithorax (Ubx)
Hox genes regionalize the animal body axis by modifying complex morphogenetic and differentiation processes during development. The transformation of wings into halteres by the Hox gene Ultrabithorax (Ubx) in Drosophila melanogaster presents an excellent model system to study the transcriptional net...
ORGANISM(S): Drosophila melanogaster 
2010-12-31 | E-GEOD-22354 | biostudies-arrayexpress
UnknownDomain Organization of the UBX Domain Containing Protein 9 and Analysis of Its Interactions With the Homohexameric AAA + ATPase p97 (Valosin-Containing Protein).
Not available
S-EPMC8495200 | biostudies-literature
UnknownThe ubiquitin regulatory X (UBX) domain-containing protein TUG regulates the p97 ATPase and resides at the endoplasmic reticulum-golgi intermediate compartment.
Not available
S-EPMC3307297 | biostudies-literature
ProteomicsComparative proteome-wide abundance profiling of yeast strains deleted for Cdc48 adaptors
The yeast ATPase Cdc48 (known as p97/VCP in human cells) plays an important role in the Ubiquitin Proteasome System. VCP is essential for cancer cell proliferation and its dysregulation has been implicated in several neurodegenerative diseases. Cdc48 functions by extracting ubiquitylated proteins fr...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-05-07 | PXD055137 | Pride
Ubiquitin proteasome system S. cerevisiae Ubx domain-containing proteins Tmt proteomics Cdc48 Proteome 
UnknownVersatile control of the CDC48 segregase by the plant UBX-containing (PUX) proteins.
Not available
S-EPMC8181520 | biostudies-literature
UnknownA novel UBA and UBX domain protein that binds polyubiquitin and VCP and is a substrate for SAPKs.
Not available
S-EPMC1134123 | biostudies-literature
UnknownComplex of Fas-associated factor 1 (FAF1) with valosin-containing protein (VCP)-Npl4-Ufd1 and polyubiquitinated proteins promotes endoplasmic reticulum-associated degradation (ERAD).
Not available
S-EPMC3591610 | biostudies-literature
UnknownThe structural and functional basis of the p97/valosin-containing protein (VCP)-interacting motif (VIM): mutually exclusive binding of cofactors to the N-terminal domain of p97.
Not available
S-EPMC3207442 | biostudies-literature
GenomicsmodENCODE_White Lab: genome-wide ChIP data of Ubx from E0-12 on Illumina Genome Analyzer.
This is a dataset generated by the Drosophila Regulatory Elements modENCODE Project led by Kevin P. White at the University of Chicago. It contains genome-wide binding profile of the factor Ubx from E0-12 generated by ChIP and analyzed on Illumina Genome Analyzer. For data usage terms and condition...
ORGANISM(S): Drosophila melanogaster 
2011-12-28 | E-GEOD-34708 | biostudies-arrayexpress
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