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NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7251 | MetaboLights

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7253 | MetaboLights

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7252 | MetaboLights
Proteomic analysis to reveal the effect on growth of soybean seeds radiated millimeter-wave
ORGANISM(S): Glycine Max 
This work aims to detect the differentially expressed proteins between transferrin receptor 1 inhibition and iron chelation in a natural killer cell lymphoma-derived cell line NK92. Cells were treated with 500 μM deferoxamine or 10 μg/mL PPMX-T003 (an anti-transferrin receptor 1 inhibitory antibody)...
ORGANISM(S): Homo Sapiens (human) 
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