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TranscriptomicsDynamics of intercellular and extracellular (exosomal) miRNAs in hypoxic RPMI8226 cells
Recently, the existence of extracellular miRNAs enclosed in exosomes has raised the possibility that they play an important role in cell-cell communication. To gain more insight into cell-cell communication via exosomal miRNAs, we investigated whether or not tumor cells exposed to hypoxia secrete ex...
ORGANISM(S): Homo sapiens 
2013-12-03 | E-GEOD-45388 | biostudies-arrayexpress
TranscriptomicsDynamics of intercellular and extracellular (exosomal) miRNAs in hypoxic SUDHL4 cells
Recently, the existence of extracellular miRNAs enclosed in exosomes has raised the possibility that they play an important role in cell-cell communication. To gain more insight into cell-cell communication via exosomal miRNAs, we investigated whether or not tumor cells exposed to hypoxia secrete ex...
ORGANISM(S): Homo sapiens 
2013-12-03 | E-GEOD-45387 | biostudies-arrayexpress
TranscriptomicsDynamics of intercellular and extracellular (exosomal) miRNAs in hypoxic K562 cells
Recently, the existence of extracellular miRNAs enclosed in exosomes has raised the possibility that they play an important role in cell-cell communication. To gain more insight into cell-cell communication via exosomal miRNAs, we investigated whether or not tumor cells exposed to hypoxia secrete ex...
ORGANISM(S): Homo sapiens 
2013-12-03 | E-GEOD-45289 | biostudies-arrayexpress
TranscriptomicsExpression profiling in cellular miRNAs of human bone marrow stromal cells
The aging of bone marrow stromal cells (BMSCs) lead to decreased ability to maintain hematopoiesis. The aim of this study is therefore to determine the age-related change of cellular miRNAs in BMSCs. Human BMSCs of young (yBMSC s, age of donors: 19 and 20 years) and elderly (eBMSC s, age of donors: ...
ORGANISM(S): Homo sapiens 
2017-05-12 | E-GEOD-78866 | biostudies-arrayexpress
TranscriptomicsExpression profiling in exosomal miRNAs secreted from human bone marrow stromal cells
The aging of bone marrow stromal cells (BMSCs) lead to decreased ability to maintain hematopoiesis, however, effects of aging on BMSC-derived exosomes in bone marrow microenvironment remain unclear. The aim of this study is therefore to determine the age-related change of BMSC-derived exosomal miRNA...
ORGANISM(S): Homo sapiens 
2017-05-12 | E-GEOD-78865 | biostudies-arrayexpress
TranscriptomicsComparison of normalized signal intensities of various miRNAs in the exsosomes isolated by Exoquick or ultracentrifugation
MicroRNAs (miRNAs), small (18–22 nucleotides) non-coding RNAs, suppress the translation of target mRNAs by binding to their 3′ untranslated region. Evidence suggests that miRNAs are key regulators of several cellular processes, including angiogenesis. Recent findings indicate that Secreted miRNAs en...
ORGANISM(S): Homo sapiens 
2012-01-26 | E-GEOD-35256 | biostudies-arrayexpress
TranscriptomicsDynamics of intercellular and exosomal miRNAs in hypoxia-resistant KMS-11 cells
In multiple myeloma (MM), abnormal plasma cells interact with bone marrow (BM) stromal cells and vascular cells among others. A part of the BM milieu is considered highly hypoxic, and myeloma cells in situ may be influenced by circumstances other than normoxia in vitro. Hence, we attempted to confir...
ORGANISM(S): Homo sapiens 
2014-10-15 | E-GEOD-48908 | biostudies-arrayexpress
TranscriptomicsDynamics of intercellular and exosomal miRNAs in hypoxia-resistant U266 cells
In multiple myeloma (MM), abnormal plasma cells interact with bone marrow (BM) stromal cells and vascular cells among others. A part of the BM milieu is considered highly hypoxic, and myeloma cells in situ may be influenced by circumstances other than normoxia in vitro. Hence, we attempted to confir...
ORGANISM(S): Homo sapiens 
2014-10-15 | E-GEOD-48910 | biostudies-arrayexpress
TranscriptomicsDynamics of intercellular and exosomal miRNAs in hypoxia-resistant RPMI8226 cells
In multiple myeloma (MM), abnormal plasma cells interact with bone marrow (BM) stromal cells and vascular cells among others. A part of the BM milieu is considered highly hypoxic, and myeloma cells in situ may be influenced by circumstances other than normoxia in vitro. Hence, we attempted to confir...
ORGANISM(S): Homo sapiens 
2014-10-15 | E-GEOD-48909 | biostudies-arrayexpress
TranscriptomicsDynamics of intercellular and exosomal miRNAs in hypoxia-resistant cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-10-15 | E-GEOD-48983 | biostudies-arrayexpress
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