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TranscriptomicsSepsis induces long-lasting impairments in T helper cell responses despite rapid numerical recovery of T-lymphocyte populations
Our experiments examined T-lymphocyte numbers and effector-functions in peritoneal contamination and infection (PCI) a mouse model of sepsis. One of our main questions was how T-lymphocytes reconstitute after sepsis-induced lymphopenia. We investigated the quantitative and qualitative recovery of T ...
ORGANISM(S): Mus musculus 
2019-10-02 | E-MTAB-7483 | biostudies-arrayexpress
TranscriptomicsDisruption of KCC2 in parvalbumin-positive interneurons causes fatal epilepsy in mice
Since many years, we are interested in the regulation of the intraneuronal chloride concentration. We were the first group reporting a full knockout of the KCl-co-transporter KCC2, which dies immediately after birth due to respiratory failure. Notably, KCC2 loss-of-function mutations are associated ...
ORGANISM(S): Mus musculus 
2022-11-02 | E-MTAB-11147 | biostudies-arrayexpress
UnknownGenetic landscape of congenital insensitivity to pain and hereditary sensory and autonomic neuropathies.
Not available
S-EPMC10689924 | biostudies-literature
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