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TranscriptomicsLOC283731 promoter hypermethylation prognosticates survival after radiochemotherapy in IDH1 wild-type glioblastoma patients
MGMT promoter methylation status is currently the only established molecular prognosticator in IDH wild-type glioblastoma multiforme (GBM). Therefore, we aimed to discover novel therapy-associated epigenetic biomarkers. After enrichment for hypermethylated fractions using methyl-CpG-immunoprecipitat...
ORGANISM(S): Homo sapiens 
2016-03-10 | E-GEOD-74561 | biostudies-arrayexpress
GenomicsWhole-genome sequencing analysis of low-grade astrocytomas within the ICGC PedBrain Tumor Project
In order to investigate the full range of genetic alterations contributing to the tumourigenesis of low-grade astrocytoma, we have conducted a next-generation sequencing-based analysis on a large series of matched tumor-normal pairs. This study, conducted by the International Cancer Genome Consortiu...
EGAS00001000381 | EGA
GenomicsDATA_SET_ICGC_PedBrainTumor_Medulloblastoma_Discovery_Cohort - samples
DATA_SET_ICGC_PedBrainTumor_Medulloblastoma
EGAD00001000122 | EGA
GenomicsWGS-SEQ_DATA_SET_rain_PA_2012_10_22 - samples
Pilocytic Astrocytoma ICGC PedBrain whole genome sequencing
EGAD00001000616 | EGA
GenomicsRNA-SEQ_DATA_SET_rain_PA_2012_10_22 - samples
Pilocytic Astrocytoma ICGC PedBrain RNA sequencing
EGAD00001000617 | EGA
GenomicsDATA_SET_ICGC_PedBrain_Tumor_Low-Grade_Astrocytoma_Study - samples
Pilot study Pilocytic Astrocytoma ICGC PedBrain, whole genome sequencing of 5 tumors and matched blood
EGAD00001000271 | EGA
TranscriptomicsIntegrated epigenetic and copy-number profiling identifies three clinically and biologically relevant groups of anaplastic glioma
The outcome of patients with anaplastic gliomas varies considerably depending on histology and single molecular markers such as codeletion of 1p/19q and mutations of the isocitrate dehydrogenase (IDH) gene. Whether a molecularly-based classification of anaplastic gliomas based on large scale genomic...
ORGANISM(S): Homo sapiens 
2014-06-06 | E-GEOD-58218 | biostudies-arrayexpress
GenomicsRNA-seq_DATA_SET_ICGC_PedBrainTumor_Medulloblastoma_Discovery_Cohort - samples
ICGC PedBrain: RNA sequencing
EGAD00001000328 | EGA
GenomicsWGS_MATE_PAIR_DATA_SET_ICGC_PedBrainTumor_Medulloblastoma_Discovery_Cohort - samples
release_2: ICGC PedBrain: whole genome mate-pair sequencing
EGAD00001000327 | EGA
Genomics2013-11-19-17-24-36-breez-MB-2013-10-18-Whole_exome_DNAseq_Medulloblastoma - samples
Illumina HiSeq sequence data (with >80x coverage) were aligned to the hg19 human reference genome assembly using BWA (Li and Durbin, 2009); duplicate reads were removed from the final BAM file. No realignment or recalibration was performed. The whole exome sequencing data of 20 SHH medulloblastomas ...
EGAD00001000698 | EGA
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