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ProteomicsCharacterization of the human urinary proteome and peptidome
Urine represents an ideal source of clinically relevant biomarkers since it contains a large number of proteins and low molecular weight peptides. Characterization of the normal urinary proteome and peptidome can serve as a reference for disease and can aid in biomarker discovery. Proteomic and pept...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-21 | MSV000080263 | MassIVE
ProteomicsUrinary PRM analysis of early type 1 diabetes
Chronic hyperglycemia is known to disrupt the proteolytic milieu, initiating compensatory and maladaptive pathways in the diabetic kidney. Such changes in intrarenal proteolysis can be captured in the urinary peptidome. We thus examined the urinary peptidomes of otherwise healthy youths with type 1 ...
ORGANISM(S): Homo Sapiens 
2020-01-01 | PXD012389 | panorama
ProteomicsCharacterization of the human urinary proteome and peptidome
Urine represents an ideal source of clinically relevant biomarkers since it contains a large number of proteins and low molecular weight peptides. Characterization of the normal urinary proteome and peptidome can serve as a reference for disease and can aid in biomarker discovery. Proteomic and pept...
ORGANISM(S): Homo sapiens (Human) 
2016-07-12 | PXD003595 | Pride
Human Peptidomics Proteomics Peptide sequence alignment Protease activity analysis Urinary proteome Urinary peptidome Urine Lc-ms/ms 
UnknownUrine peptidome analysis in cardiorenal syndrome reflects molecular processes.
Not available
S-EPMC8355128 | biostudies-literature
ProteomicsUrinary polypeptide ETD/CID analysis, part 2
Urine as a biofluid is commonly used in clinical diagnostics, including those performed during pregnancy. Urine is a rich source of polypeptides and protein degradation products, which have been filtered from blood plasma, thus urine has strong potential as a source for novel clinical diagnostics in...
ORGANISM(S): Homo sapiens (Human) 
2016-02-15 | PXD002346 | Pride
Urine Pregnancy Non-tryptic peptides Peptidome Electron transfer dissociation 
ProteomicsUrinary polypeptide ETD/CID analysis, part 3
Urine as a biofluid is commonly used in clinical diagnostics, including those performed during pregnancy. Urine is a rich source of polypeptides and polypeptidic protein degradation products, which have been filtered from blood plasma, thus urine has potential as a source for novel clinical diagnost...
ORGANISM(S): Homo sapiens (Human) 
2016-02-15 | PXD002372 | Pride
Urine Pregnancy Non-tryptic peptides Peptidome Electron transfer dissociation 
UnknownUrinary peptidome analysis in CKD and IgA nephropathy.
Not available
S-EPMC10616486 | biostudies-literature
UnknownExploratory Study Analyzing the Urinary Peptidome of T2DM Patients Suggests Changes in ECM but Also Inflammatory and Metabolic Pathways Following GLP-1R Agonist Treatment.
Not available
S-EPMC10488289 | biostudies-literature
ProteomicsUrinary Glycosylated IGF2 peptides in association with CKD
Chronic kidney disease (CKD) is prevalent in 10% of world’s adult population, with Estimated Glomerular filtration rate (eGFR) and albuminuria employed in diagnosis. Role of protein glycosylation in causal mechanisms of CKD progression is largely unknown. Aim of this study was to identify urinary O-...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD039829 | Pride
Ckd  egfr  post translational modifications  ptms  glycosylation  urine  peptidomics  glyco-peptide  igf2 
ProteomicsUrinary polypeptide ETD/CID analysis, part 1
Urine as a biofluid is commonly used in clinical diagnostics, including those performed during pregnancy. Urine is a rich source of polypeptides and protein degradation products, which have been filtered from blood plasma, thus urine has strong potential as a source for novel clinical diagnostics in...
ORGANISM(S): Homo sapiens (Human) 
2016-02-15 | PXD002312 | Pride
Human urine etd cid 
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