Sort   by:  
 Page size 
MetabolomicsIntegrated multi-omics of feces, plasm aand urine can describe and differentiate pediatric active Crohn’s Disease from remission

Background

This study aimed to obtain a holistic view of remission in pediatric Crohn’s Disease (CD) by integrating six omics datasets from three anatomical compartments.


Methods

Patients with fecal calprotectin below 250 mg/kg were c...

2025-07-09 | MTBLS9877 | MetaboLights
MetabolomicsUPLC-Q-TOF/MS-Based Plasma and Urine Metabolomics Contribute to the Diagnosis of Sepsis
In this study, we aimed to identify potential metabolic biomarkers that can improve the diagnostic accuracy of sepsis. Sixty-six patients including 30 septic and 36 nonsepsis patients from an intensive care unit were recruited. The global plasma and urine metabolomic profiles were determined by ultr...
2023-04-18 | MTBLS3505 | MetaboLights
MetabolomicsMetabolic phenotyping of urine from a dementia research cohort
To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to studies involving hundreds and thousands of biofluid samples. Hyphenated ultra-performance liquid chromatography-mass spectromet...
2022-03-01 | MTBLS719 | MetaboLights
ProteomicsUrine Proteomics for Noninvasive Monitoring of Biomarkers in Bronchopulmonary Dysplasia
Current techniques to diagnose and/or monitor critically ill neonates with bronchopulmonary dysplasia (BPD) require invasive sampling of body fluids, which can affect the health status of these frail neonate. We tested our hypotheses 1) it is feasible to use early urine samples from extremely low g...
ORGANISM(S): Homo sapiens (Human) 
2022-04-04 | PXD028895 | Pride
Extremely low gestational age newborn Mass spectrometry Chronic lung disease 
MetabolomicsEx-Vivo Equine Cartilage Explant Osteoarthritis Model - A Metabolomics and Proteomics Study
Osteoarthritis (OA) is an age-related degenerative musculoskeletal disease characterised by loss of articular cartilage, synovitis, abnormal bone proliferation and subchondral bone sclerosis. Underlying OA pathogenesis is yet to be fully elucidated with no OA specific biomarkers in clinical use. Ex-...
2020-09-30 | MTBLS1495 | MetaboLights
ProteomicsIntact Glycopeptide Analysis of Human Urine
Identification of intact glycopeptides in pooled healthy human urine samples
ORGANISM(S): Homo sapiens (Human) 
2024-02-21 | PXD038923 | Pride
Urine Glycoproteomics Human Lc-ms/ms 
ProteomicsSpatiotemporal proteomics of hormone treated mice (urine across time, prostate tissue)
Benign prostatic hyperplasia and related lower urinary tract symptoms remain common, costly, and impactful issues for aging males. Etiology and pathogenesis are multifactorial and include steroid hormone changes and inflammation. Noninvasive markers could one day inform personalized medicine, but in...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-08 | PXD014416 | Pride
Mus musculus Urine Proteomics Hormone Prostate 
MetabolomicsTargeted metabolomic analysis in hepatic extracts, serum, and urine of female mice gavaged with TCDD every 4 days for 28 days
TCDD is an environmental contaminant that elicits a number of hepatic effects including fat accumulation, inflammation, and fibrosis that can progress to hepatocellular carcinoma. RNA-Seq and targeted metabolomics were integrated with complementary dioxin response element (DRE) location and aryl hyd...
2017-02-02 | MTBLS225 | MetaboLights
ProteomicsUrine proteomics as a source of biological information and outcome predictor in living kidney transplantation
Kidney transplantation is the preferred treatment for kidney failure, offering improved survival, quality of life and cost-effectiveness compared to dialysis. However, post-transplant management is challenging due to the limited lifespan of transplanted organs, often requiring repeat transplants. Cu...
ORGANISM(S): Homo sapiens (Human) 
2026-04-01 | PXD057361 | Pride
Kidney transplantation Urine proteomics 
ProteomicsUrine proteomics as a source of biological information and outcome predictor in living kidney transplantation - Validation cohort
Kidney transplantation is the preferred treatment for kidney failure, offering improved survival, quality of life and cost-effectiveness compared to dialysis. However, post-transplant management is challenging due to the limited lifespan of transplanted organs, often requiring repeat transplants. Cu...
ORGANISM(S): Homo sapiens (Human) 
2026-04-01 | PXD071468 | Pride
Kidney transplantation Urine proteomics 
Sort   by:  
 Page size