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ProteomicsGFI1 facilitates efficient DNA repair by regulating PRMT1-dependent methylation of MRE11 and 53BP1
GFI1 is a transcriptional regulator expressed in lymphoid cells, and an "oncorequisite" factor required for development and maintenance of T-lymphoid leukemia. GFI1 deletion causes hypersensitivity to ionizing radiation, for which the molecular mechanism remains unknown. Here, we demonstrate that GF...
ORGANISM(S): Homo sapiens (Human) 
2018-10-19 | PXD008897 | Pride
Dna repair gfi1 prmt1 methylation mre11 53bp1 
TranscriptomicsExpression profiling of Mammary Gland Tumor epithelial cells
Transcriptional profiling of mammary gland tumors from transgenic mice overexpressing the p110 or p75 isoform of CUX1. RNA was extracted from epithelial cells isolated using Laser-Capture Microdissection (LCM) 9 tumors from p75-CUX1 transgenic mice and 8 tumors from p110-CUX1 mice. Biological sample...
ORGANISM(S): Mus musculus 
2014-09-15 | E-GEOD-54804 | biostudies-arrayexpress
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