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ProteomicsKidney proteomics in the unilateral ureter obstruction (UUO) mouse model
Treatments for kidney fibrosis represent an urgent yet unmet clinical need. Effective therapies are limited due to not well understood molecular pathogenesis. We aimed at generating a comprehensive and integrated multi-omics data set (RNA/ microRNA transcriptomics and proteomics) of fibrotic kidneys...
ORGANISM(S): Mus musculus (Mouse) 
2019-05-09 | PXD010861 | Pride
Ckd Fibrosis Mouse Kidney 
ProteomicsKidney proteomics in the folic acid (FA) induced nephropathy mouse model
Treatments for kidney fibrosis represent an urgent yet unmet clinical need. Effective therapies are limited due to not well understood molecular pathogenesis. We aimed at generating a comprehensive and integrated multi-omics data set (RNA/ microRNA transcriptomics and proteomics) of fibrotic kidneys...
ORGANISM(S): Mus musculus (Mouse) 
2019-05-09 | PXD011453 | Pride
Ckd Fibrosis Mouse Kidney 
ProteomicsDrug Induced Liver Injury Biomarker Discovery Data
Discovery proteomics was conducted on serum samples using tandem mass tagging for relative quantitation to discover potential new biomarkers of DILI.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-07-01 | MSV000089782 | MassIVE
ProteomicsTandem Mass Tag-Based Quantitative Proteomic Profiling Identifies Novel Serum Biomarkers of Drug-Induced Liver Injury in Humans
Diagnosis of drug-induced liver injury (DILI) and its distinction from other liver diseases are significant challenges in drug development and clinical practice. In this study we identify, confirm, and replicate the biomarker performance characteristics of candidate proteins in a cohort of patients ...
ORGANISM(S): Homo Sapiens 
2024-01-04 | PXD034882 | panorama
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