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TranscriptomicsGenome-wide gene expression analysis of MDA-MB-468 human breast cancer cells treated with PLA2G7 shRNA
The aim was to investigate the functional role of PLA2G7 in breast cancer using PLA2G7 silencing in cultured breast cancer cells. For stable knockdown of PLA2G7, shRNAs were transduced to MDA-MB-468 cells before genome-wide gene expression analysis. Gene expression profiles of the PLA2G7 silenced sa...
ORGANISM(S): Homo sapiens 
2017-06-02 | E-MTAB-5398 | biostudies-arrayexpress
TranscriptomicsGenome-wide gene expression analysis of MDA-MB-468 human breast cancer cells treated with PLA2G7 siRNA
The aim was to investigate the functional role of PLA2G7 in breast cancer using transient PLA2G7 silencing in cultured breast cancer cells. For transient knockdown of PLA2G7, siRNA (SI00072177; siPLA2G7, Qiagen, Valencia, CA) was transfected to MDA-MB-468 cells and incubated 48 hours before genome-w...
ORGANISM(S): Homo sapiens 
2017-06-02 | E-MTAB-5397 | biostudies-arrayexpress
TranscriptomicsPhospholipase PLA2G7 is a drug target and a potent biomarker in prostate cancer
Effects of siRNA treatment on gene expression in VCaP prostate cancer cell line
ORGANISM(S): Homo sapiens 
2012-01-04 | E-TABM-1172 | biostudies-arrayexpress
TranscriptomicsIntegrative genomic, transcriptomic and RNAi analysis indicates a potential oncogenic role for FAM110B in castration-resistant prostate cancer.
Background: Castration-resistant prostate cancer (CRPC) represents a therapeutic challenge for current medications. Methods: In order to explore the molecular mechanisms involved in CRPC progression and to identify new therapeutic targets, we analyzed a unique sample set of 11 castration-resistant p...
ORGANISM(S): Homo sapiens 
2011-08-28 | E-GEOD-28403 | biostudies-arrayexpress
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