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TranscriptomicsHypoxia-responsive gene expression profile of U87 MG glioblastoma cells and their exosomes.
How cancer cells adapt to hypoxia during tumor development remains an important question. The hypothesis tested in the present study was that tumor cell-derived exosome vesicles (also known as microvesicles or extracellular vesicles) are mediators of hypoxia-dependent intercellular signaling in gli...
ORGANISM(S): Homo sapiens 
2013-03-20 | E-GEOD-45301 | biostudies-arrayexpress
TranscriptomicsIdentification of discriminant genes and gene networks involved in pig ovarian follicular atresia
Folliculogenesis corresponds to the development of follicles leading to either ovulation or degeneration (a process called atresia). Even if atresia involves an apoptosis process, this mechanism is not well understood. The objective of this experiment was : 1) to analyse gene expression in pig granu...
ORGANISM(S): Sus scrofa 
2010-06-24 | E-GEOD-7635 | biostudies-arrayexpress
TranscriptomicsThe HER2-encoded miR-4728-3p regulates ESR1 through a non-canonical internal seed interaction
Since the early 1980s remarkable progress has been made in understanding the role of the HER2 locus in carcinogenesis, but many details of its regulatory network are still elusive. We recently reported the finding of 367 new human microRNA (miRNA) genes of which one, mir-4728, is encoded in an intro...
ORGANISM(S): Homo sapiens 
2014-08-13 | E-GEOD-55822 | biostudies-arrayexpress
TranscriptomicsIn vivo gene expression in granulosa cells during pig terminal follicular development- oligo
These vector oligonucleotide hybridizations were performed to determine the quality of the spotting process. EST with low signal values of the vector array were excluded from the analysis, since they probably were mis-amplified or mis-spotted Keywords: spotting control cDNA arrays (GPL3978) were fi...
ORGANISM(S): Sus scrofa 
2008-04-30 | E-GEOD-5797 | biostudies-arrayexpress
UnknownThe complete mitochondrial genome sequence of the green microalga Lobosphaera (Parietochloris) incisa reveals a new type of palindromic repetitive repeat.
Not available
S-EPMC4524435 | biostudies-literature
TranscriptomicsIn vivo gene expression in granulosa cells during pig terminal follicular development.
The aim of this study is the identification of genes and gene networks involved in pig ovarian follicular development. cDNA nylon micro-arrays (2849 sequenced clones) were designed from different libraries : four subtractive suppressive hybridization libraries (generated from small versus large and ...
ORGANISM(S): Sus scrofa 
2008-04-30 | E-GEOD-5798 | biostudies-arrayexpress
UnknownDevelopment of a nuclear transformation system for Oleaginous Green Alga Lobosphaera (Parietochloris) incisa and genetic complementation of a mutant strain, deficient in arachidonic acid biosynthesis.
Not available
S-EPMC4136796 | biostudies-literature
TranscriptomicsNon-coding antisense transcription detected by conventional and single-stranded cDNA microarray
Recent bioinformatic studies revealed that many mammalian protein-coding genes also transcribe their complementary strands. This phenomenon raises questions regarding the validity of data obtained from double-stranded cDNA microarrays since hybridization to both strands may occur. To analyze experim...
ORGANISM(S): Homo sapiens 
2007-09-01 | E-GEOD-7860 | biostudies-arrayexpress
TranscriptomicsThe non-coding RNA of the multidrug resistance-linked vault particle encodes multiple regulatory small RNAs
Vault particles are conserved organelles that have been implicated in multidrug resistance and intracellular transport. They are formed by three different proteins and the non-coding vault RNAs (vRNAs). Here we show that human vRNAs produce several small RNAs (svRNAs) by mechanisms different from th...
ORGANISM(S): Homo sapiens 
2009-09-07 | E-GEOD-16060 | biostudies-arrayexpress
TranscriptomicsTasquinimod, a Quinoline-3-Carboxamide Anti-Angiogenic Agent, treated Prostate Cancer Cell Line in-vivo and in-vitro
The quinoline-3-carboxamide ABR-215050 (Tasquinimod (INN)), exhibits anti-tumor activity via inhibition of tumor angiogenesis in human and rodent tumors. To further explore the mode of action of ABR-215050, in vivo experiments with gene microarray analysis were performed using samples of LNCaP prost...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-GEOD-17031 | biostudies-arrayexpress
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