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ProteomicsUrinary proteomics in youths with and without type 1 diabetes
Diabetic kidney disease is the leading cause of end-stage renal disease worldwide. Our understanding of the early kidney response to chronic hyperglycemia remains incomplete. In this study, we aimed to uncover the early, dysregulated pathways in the diabetic kidney before the onset of microalbuminur...
ORGANISM(S): Homo sapiens (Human) 
2020-06-01 | PXD017213 | Pride
Proteomics Urine Type 1 diabetes 
ProteomicsUrinary peptidomics in youths with and without type 1 diabetes
Although the early mechanisms responsible for diabetic kidney disease remain unclear, it is widely believed that chronic hyperglycemia disrupts the proteolytic milieu in the diabetic kidney and may contribute to early kidney injury. We thus performed mechanistic peptidomics in type 1 diabetes before...
ORGANISM(S): Homo sapiens (Human) 
2020-01-20 | PXD012210 | Pride
Human Peptidomics Urine Type 1 diabetes Lc-ms/ms 
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