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TranscriptomicsReactivation of multipotency by oncogenic PIK3CA induces breast tumor heterogeneity
Breast cancer is the most frequent cancer in women and consists of heterogeneous types of tumours that are classified into different histological and molecular subtypes1-3. Pik3ca and p53 are the two most frequently mutated genes and are associated with different types of human breast cancers4. The ...
ORGANISM(S): Mus musculus 
2015-08-13 | E-GEOD-69290 | biostudies-arrayexpress
TranscriptomicsRNA-seq of murine mammary epithelial cells from ovariectomised females treated with estradiol (E2) or estetrol (E4)
To mimick menopause hormone therapy and compare the effects of estetrol (E4) to the ones of estradiol (E2), ovariectomized mice were treated for 2 weeks with E2, a physiological dose of E4 (E4low) or a supra physiological dose of E4 (E4hi). Non treated ovariectomized mice were used as control. Basal...
ORGANISM(S): Mus musculus 
2026-06-01 | E-MTAB-16111 | biostudies-arrayexpress
TranscriptomicsRNA-seq of murine vagina and uterus epithelial cells from ovariectomised females treated with estradiol (E2) or estetrol (E4) with different dose
To mimic menopause hormone therapy and compare the effects of estetrol (E4) to the ones of estradiol (E2), ovariectomized mice were treated for 2 weeks with E2, a physiological dose of E4 (E4low) or a supra physiological dose of E4 (E4hi). Non treated ovariectomized mice were used as control. Epithe...
ORGANISM(S): Mus musculus 
2026-06-01 | E-MTAB-16112 | biostudies-arrayexpress
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