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TranscriptomicsTranscriptomic profiling of three different neuroblastoma cell lines (CLB-BAR, CLB-GE and SK-N-AS) in response to ALK inhibition
Anaplastic Lymphoma Kinase (ALK) is a tyrosine kinase receptor which is a clinical target of major interest in cancer, including neuroblastoma. To better understand ALK signaling, three different neuroblastoma cell lines (CLB-BAR, CLB-GE and SK-N-AS) were cultured for 1hr and 24hrs in control condit...
ORGANISM(S): Homo sapiens 
2018-09-01 | E-MTAB-6654 | biostudies-arrayexpress
TranscriptomicsRNA-seq of neuroblastoma mouse model (Alk-F1178S;Th-MYCN) after treatment with the ATR inhibitor ceralasertib
To understand the in vivo transcriptomic response to ATR inhibition, RNA-Seq was performed 3 days after treatment of a previously developed neuroblastoma mouse model (Alk-F1178S;Th-MYCN; see Borenas et al., EMBO J, 2021) with the ATR inhibitor ceralasertib.
ORGANISM(S): Mus musculus 
2023-11-30 | E-MTAB-12961 | biostudies-arrayexpress
TranscriptomicsRNA-seq of neuroblastoma mice models after treatment with the ATR inhibitor BAY 1895344
To understand the in vivo transcriptomic response to ATR inhibition, RNA-Seq was performed after treatment of 2 previously developed neuroblastoma mouse models (Alk-F1178S;Th-MYCN and Rosa26_Alkal2;Th-MYCN; see Borenas et al., EMBO J, 2021) with the ATR inhibitor BAY 1895344.
ORGANISM(S): Mus musculus 
2021-10-21 | E-MTAB-10616 | biostudies-arrayexpress
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