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TranscriptomicsTranscription profiling of mouse intestinal epithelial spheroids cultured as stem cells, wound-associated epithelial cells or enterocytes
Intestinal epithelial spheroids were isolated from mouse jejunum as described in our previous publication (Miyoshi and Stappenbeck. In vitro expansion and genetic modification of gastrointestinal stem cells in spheroid culture. Nature Protocols. 2013. PMID: 24232249) and then grown in 50% L-WRN cond...
ORGANISM(S): Mus musculus 
2016-10-25 | E-MTAB-3952 | biostudies-arrayexpress
Transcriptomics16S rRNA sequencing of cecal microbiota from neonatal mice pre- and post-weaning
Neonatal mice were susceptible to cryptosporidium infection at 1- and 2-weeks of age, but were resistant to infection at 3- and 6-weeks of age. Diet and microbial changes are known to occur during the weaning transition in mice and we hypothesized that these changes in the intestinal luminal environ...
ORGANISM(S): mouse gut metagenome 
2020-11-03 | E-MTAB-9100 | biostudies-arrayexpress
TranscriptomicsRNA-seq of formalin-fixed, paraffin-embedded uninvolved terminal ileal tissue obtained from ileo-colic resection surgeries of Crohns disease and control patients
The interpretation of transcriptional profiling studies of intestinal tissue from Crohns disease patients and control patients can be confounded by differing proportions of cell subsets (e.g. immune cells) present in these samples. In this study, we aimed to control for cellular composition using st...
ORGANISM(S): Homo sapiens 
2018-05-22 | E-MTAB-5783 | biostudies-arrayexpress
TranscriptomicsMicroarray of formalin-fixed, paraffin-embedded uninvolved terminal ileal tissue obtained from ileo-colic resection surgeries of Crohn’s disease and control patients
The interpretation of transcriptional profiling studies of intestinal tissue from Crohn’s disease patients and control patients can be confounded by differing proportions of cell subsets (e.g. immune cells) present in these samples. In this study, we aimed to control for cellular composition using s...
ORGANISM(S): Homo sapiens 
2018-05-22 | E-MTAB-5790 | biostudies-arrayexpress
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