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UnknownRIPK1 ablation in T cells results in spontaneous enteropathy and TNF-driven villus atrophy
RIPK1 is a crucial regulator of cell survival, inflammation and cell death. Human RIPK1 deficiency leads to early-onset intestinal inflammation and peripheral T cell imbalance, though its role in αβT cell mediated intestinal homeostasis remains unclear. In this study, we demonstrate that mice with R...
S-SCDT-10_1038-S44319-025-00441-5 | biostudies-other
TranscriptomicsRNA-seq of CD8 single positive thymocytes from WT and Rela fx/fx CD4Cre Nfkb1KO RelKO mice.
Gene expression by CD8 thymocytes was compared between cells from WT mice, and cell from mice with gremlin deletions of cRel and Nfkb1, and a T cell specific deletion of Rel using CD4 Cre.
ORGANISM(S): Mus musculus 
2019-08-23 | E-MTAB-7470 | biostudies-arrayexpress
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