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TranscriptomicsGenome-wide analysis of gene expression in VAV1-/- versus VAV1+/+ bone marrow (BM)-macrophages
Analysis of differential gene expression profiles in VAV1-/- versus VAV+/+ BM-macrophages , respectively. A distinct expression profile in VAV1-/- versus VAV1+/+ (wild-type) BM-macrophages allows to resolve molecular mechanisms. Total RNA was obtained froms BM-macrophages of VAV1+/+ and VAV1-/- mic...
ORGANISM(S): Mus musculus 
2013-03-08 | E-GEOD-36123 | biostudies-arrayexpress
GenomicsVav Knockout in Raw264.7 macrohages
Vav Knockout in Raw264.7 macrohages
PRJNA517437 | ENA
TranscriptomicsDifferential gene expression analysis of fetal liver cells of R26-LSL-KITD816V:Vav-iCre mice related to controls
Analysis of differential gene expression. The influence of a constitutively activated mutant Kit receptor on gene expression in fetal hematopoietic cells was analyzed. Results provide information of genes and cellular processes that are influenced by Kit signaling. Total RNA obtained from embryonic ...
ORGANISM(S): Mus musculus 
2014-10-17 | E-GEOD-53581 | biostudies-arrayexpress
TranscriptomicsVav proteins orchestrate a keratinocyte auto/paracrine program critical for skin tumorigenesis.
Cutaneous squamous tumors rely on autocrine/paracrine loops for proper fitness. Targeting this Achilles’ heel is therefore considered a potential avenue for patient treatment. However, the mechanisms that engage and sustain such programs during tumor ontogeny are poorly understood. Here, we show ...
ORGANISM(S): Mus musculus 
2013-07-30 | E-GEOD-40849 | biostudies-arrayexpress
UnknownBiological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins.
Not available
S-EPMC84867 | biostudies-literature
TranscriptomicsGene expression profiling in Vav-Etv2 KSL and Granulocyte hematopoietic cells
Etv2 transgene was expressed from ROSA26 locus by removing floxed STOP cassette by Vav Cre transgene. KSL or Mac1+/Gr1+ cells were sorted from control or Vav-Etv2 bone marrow and compared for gene expression in duplicate. This study will reveal the effect of Etv2 transgene in adult hematopoietic cel...
ORGANISM(S): Mus musculus 
2012-05-09 | E-GEOD-36731 | biostudies-arrayexpress
TranscriptomicsVav Knockout in Raw264.7 macrohages
The scavenger receptor CD36 plays critical roles in lipid uptake and triggering of inflammatory response, via activation of guanine nucleotide exchange factor Vav. We used microarrays to detail the different up-regulated or down-regulate genes among three vav familymembers.
ORGANISM(S): Mus musculus 
2019-01-29 | GSE125746 | GEO
UnknownVav family proteins couple to diverse cell surface receptors.
Not available
S-EPMC86111 | biostudies-literature
GenomicsRNA-seq analysis of LSK from Oga(Vav-Cre) mice compared to wildtype
RNA-seq analysis of LSK from Oga(Vav-Cre) mice compared to wildtype
PRJNA479527 | ENA
UnknownVav proteins control MyD88-dependent oxidative burst.
Not available
S-EPMC1852252 | biostudies-literature
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