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TranscriptomicsTranscription profiling of mouse TSC2-/- embryonic fibroblasts: vehicle-treated, rapamycin-treated, gfp-infected, and pgc-1alpha-infected samples reveals the mTOR pathway controls mitochondrial gene expression and respiration through the YY1/PGC-1alpha transcriptional complex
Mitochondrial oxidative function is tightly controlled to maintain energy homeostasis in response to nutrient and hormonal signals. An important cellular component in the energy sensing response is the target of rapamycin (TOR) kinase pathway; however whether and how mTOR controls mitochondrial oxid...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-5332 | biostudies-arrayexpress
MetabolomicsAntibiotics create a shift from mutualism to competition in human gut communities with a longer-lasting impact on fungi than bacteria

Background

Antibiotic treatment has a well-established detrimental effect on the gut bacterial composition, but effects on the fungal community are less clear. Bacteria in the lumen of the gastrointestinal tract may limit fungal colonization and invasion. Antibiotic drugs t...

2020-09-28 | MTBLS1846 | MetaboLights
TranscriptomicsTranscription profiling of human lymphoblastoid cells from individuals with autism and duplication of 15q11-13autism with dup(15q)
gene expression profiles of lymphoblastoid cells from individuals with autism and duplication of 15q11-13 Experiment Overall Design: Cy5; each male with autism and dup(15q) Experiment Overall Design: Cy3; pool of 14 unrelated individuals.
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7315 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human lymphoblastoid cells from control males without autism
gene expression profiles of lymphoblastoid cells from individuals with autism and full mutation of FMR1 Experiment Overall Design: Cy5; each individual with autism and FMR1FM Experiment Overall Design: Cy3; pool of 14 unrelated individuals.
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7316 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human lymphoblastoid cells from control males without autism
gene expression profiles of lymphoblastoid cells from control males without autism Experiment Overall Design: Cy5; each control male Experiment Overall Design: Cy3; pool of 14 unrelated individuals.
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7317 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human lymphoblastoid cells (GEO Super Series)
This SuperSeries is composed of the following subset Series:; GSE7315: autism with dup(15q); GSE7316: autism with FMR1FM; GSE7317: control males Experiment Overall Design: Refer to individual Series
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7329 | biostudies-arrayexpress
UnknownThe IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p.
Not available
S-EPMC4886428 | biostudies-literature
ProteomicsThe B Cell Repertoire in Multiple Sclerosis Reveals Molecular Mimicry between EBNA1 and GlialCAM
This data set contains the mass spectrometry raw files for the paper The B Cell Repertoire in Multiple Sclerosis Reveals Molecular Mimicry between EBNA1 and GlialCAM. In multiple sclerosis (MS) intrathecal B lymphocytes are directly involved in inflammation and secrete oligoclonal immunoglobulin. Ho...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-02-11 | MSV000086842 | MassIVE
UnknownTherapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19.
Not available
S-EPMC8362594 | biostudies-literature
TranscriptomicsRecurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy [GPL6984]
STAG2 is a novel UBC tumor suppressor acting through mechanisms that are different from its role to prevent aneuploidy Gene copy number analyses of STAG2 in urinary bladder tumors. R values were extracted from beadstudio and normalised using the pounds method. Log R Ratios were calculated using an a...
ORGANISM(S): Homo sapiens 
2013-10-24 | E-GEOD-51589 | biostudies-arrayexpress
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