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MetabolomicsOverexpression of Brassica napus COMT1 in Arabidopsis heightens UV-B-mediated resistance to Plutella xylostella herbivory

UV-B radiation regulates numerous morphogenic, biochemical and physiological responses in plants, and can stimulate some responses typically associated with other abiotic and biotic stimuli, including invertebrate herbivory. Removal of UV-B from the growing environment of various plant species ha...

2023-08-14 | MTBLS8236 | MetaboLights
TranscriptomicsQuercetin induces hepatic lipid omega-oxidation and lowers serum lipid levels in mice
Elevated circulating lipid levels are known risk factors for cardiovascular diseases (CVD). In order to examine the effects of quercetin on hepatic lipid metabolism and detailed serum lipid profiles, mice received a mild-high-fat diet without (control) or with supplementation of 0.33% (w/w) querceti...
ORGANISM(S): Mus musculus 
2013-02-05 | E-GEOD-39140 | biostudies-arrayexpress
TranscriptomicsQuercetin decreases high-fat diet induced bodyweight gain and accumulation of hepatic and circulating lipids in mice.
Dietary flavonoids are supposed to be protective against cardiovascular diseases (CVD). Elevated circulating lipid levels and hepatic lipid accumulation are known risk factors for CVD. We investigated the effects and underlying molecular mechanisms of the flavonoid quercetin on hepatic lipid metabol...
ORGANISM(S): Mus musculus 
2014-10-14 | E-GEOD-51343 | biostudies-arrayexpress
UnknownQuercetin decreases high-fat diet induced body weight gain and accumulation of hepatic and circulating lipids in mice.
Not available
S-EPMC4172648 | biostudies-literature
UnknownQuercetin induces hepatic lipid omega-oxidation and lowers serum lipid levels in mice.
Not available
S-EPMC3554747 | biostudies-literature
UnknownDirect comparison of metabolic health effects of the flavonoids quercetin, hesperetin, epicatechin, apigenin and anthocyanins in high-fat-diet-fed mice.
Not available
S-EPMC4447677 | biostudies-literature
MetabolomicsGNPS MSn study of polyphenol standards
Abstract: High-mass resolution multi-stage mass spectrometry (MS(n)) fragmentation was tested for differentiation and identification of metabolites, using a series of 121 polyphenolic molecules. The MS(n) fragmentation approach is based on the systematic breakdown of compounds, forming a so-called s...
ORGANISM(S): Polyphenol Standard Compounds (reference Compounds) 
2018-01-03 | MSV000081880 | GNPS
MetabolomicsGNPS LC-MSn study of green, white, and black tea extracts
Abstract of the study: Advanced analytical approaches consisting of both LC-LTQ-Orbitrap Fourier transformed (FT)-MS and LC-time-of-flight-(TOF)-MS coupled to solid-phase extraction (SPE) NMR were used to obtain more insight into the complex phenolic composition of tea. On the basis of the combined...
ORGANISM(S): Camellia Sinensis (ncbitaxon:4442) 
2018-01-03 | MSV000081877 | GNPS
ProteomicsA PP2A-Integrator complex fine-tunes transcription by opposing CDK9
Gene expression by RNA Polymerase II (RNAPII) is tightly controlled by Cyclindependent kinases (CDKs) at discrete checkpoints during the transcription cycle. The RNAPII pausing checkpoint, engaged after transcription initiation, is controlled by CDK9 to regulate transcription in metazoans. We discov...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) Drosophila melanogaster (Fruit fly) 
2022-08-12 | PXD022962 | Pride
Cdk9 Transcription Pp2a 
MetabolomicsGNPS LC-MSn study of human urine samples containing Green Tea breakdown products
Abstract: In dietary polyphenol exposure studies, annotation and identification of urinary metabolites present at low (micromolar) concentrations are major obstacles. To determine the biological activity of specific components, it is necessary to have the correct structures and the quantification of...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-01-03 | MSV000081878 | GNPS
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