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Plitidepsin is a safe antiviral for COVID-19 patients that impairs SARS-CoV-2 replication by targeting host factors implicated in protein translation. Here we used deep quantitative proteomics coupled to infectious assays and transmission electron microscopy to dissect its antiviral activity. Plitid...
ORGANISM(S): Chlorocebus 
2024-12-19 | PXD041854 | Pride
Docetaxel is the standard first line therapy for hormone-refractory prostate cancer patients. Here we generated models of Docetaxel resistance in prostate cancer cells to study the molecular pathways that drive the acquisition of resistance to this therapy. We used microarrays to detail the global p...
ORGANISM(S): Homo sapiens 
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