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TranscriptomicsTranscription profiling of human malignant or benign breast cancer tumors to identify genes that present a differential expression between the two types of lesion
Background. Although gene expression arrays have been used to generate molecular predictors of relapse and drug sensitivity in breast cancer, no large study describes genes and exons differentially expressed between breast cancer and benign lesions.

Methods. One hundred and sixty-five tumour...
ORGANISM(S): Homo sapiens 
2009-12-30 | E-TABM-609 | biostudies-arrayexpress
TranscriptomicsIGR_MITF_STUDY_BBRB
A recent study of the characteristics of coexisting melanoma and renal cell carcinoma RCC in the same patients supports a genetic predisposition underlying the association between these two cancers. The microphthalmia associated transcription factor (MITF) was proposed to act as a melanoma oncogene;...
ORGANISM(S): Homo sapiens 
2011-09-03 | E-TABM-1198 | biostudies-arrayexpress
TranscriptomicsIGR_BREX_JF
The tissue stroma plays a major role in tumors natural history. Important programs for tumor progression such as epithelial mesenchymal transition are not activated as cell-autonomous processes but under the conditions of cross-talk between tumor and stroma. Adipose tissue is a major component of th...
ORGANISM(S): Homo sapiens 
2020-10-05 | E-MTAB-8638 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization by array of 121 paired tumor and non-tumor tissue samples from patients with non-small cell lung carcinoma to gain a systems biology insight into the current clinical classification
Non-small cell lung cancer (NSCLC), a leading cause of cancer deaths, represents a heterogeneous group of neoplasms, mostly comprising squamous cell carcinoma (SCC), adenocarcinoma (AC) and large-cell carcinoma (LCC). The aim of this study was to gain a systems biology insight into the current clini...
ORGANISM(S): Homo sapiens 
2013-12-11 | E-MTAB-1133 | biostudies-arrayexpress
TranscriptomicsIGR_CAP1_DOCETAXEL_GE_STUDY_NN
Docetaxel is used as a standard treatment in patients with metastatic castration-resistant prostate cancer. However, a large subset of patients develops resistance by mechanisms that remain largely unknown. It is thus important to define the relevant pathways implicated in docetaxel-resistance and v...
ORGANISM(S): Homo sapiens 
2013-06-30 | E-MTAB-1221 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling by array on 123 paired tumor and non-tumor tissue samples from patients with non-small cell lung carcinoma to gain a systems biology insight into the current clinical classification
Non-small cell lung cancer (NSCLC), a leading cause of cancer deaths, represents a heterogeneous group of neoplasms, mostly comprising squamous cell carcinoma (Squamous cell carcinoma), aC (AC) and large-cell carcinoma (Large cell carcinoma). The aim of this study was to gain a systems biology insig...
ORGANISM(S): Homo sapiens 
2013-12-11 | E-MTAB-1134 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array on 123 paired tumor and non-tumor tissue samples from patients with non-small cell lung carcinoma to gain a systems biology insight into the current clinical classification
Non-small cell lung cancer (NSCLC), a leading cause of cancer deaths, represents a heterogeneous group of neoplasms, mostly comprising squamous cell carcinoma (SCC), adenocarcinoma (AC) and large-cell carcinoma (LCC). The aim of this study was to gain a systems biology insight into the current clini...
ORGANISM(S): Homo sapiens 
2013-12-11 | E-MTAB-1132 | biostudies-arrayexpress
GenomicsMELARISK_SNP_MITF_geno
Genotypes at MITF E318K variant
EGAD00000000122 | EGA
GenomicsMELARISK_MITF_geno
Genotypes at MITF E318K variant
EGAD00000000121 | EGA
GenomicsA MITF germline mutation predisposes to melanoma and renal cell carcinoma
Study EGAS00000000048
EGAS00000000048 | EGA
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