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TranscriptomicsTranscriptome profiling of multiregional sampling in hepatocellular carcinoma
The purpose of this experiment is to characterize the intratumor heterogeneity in liver cancer and to study the crosstalk between the immune component of the tumor and the aberrant hepatocites.
ORGANISM(S): Homo sapiens 
2020-01-16 | E-MTAB-5905 | biostudies-arrayexpress
TranscriptomicsWhole transcriptome profiling of the vernalization process in Lilium longiflorum bulbs
We used high throughput sequencing of coding RNA to identify systematic patterns of expression during vernalization in meristems of lily bulbs that were treated with cold temperature for increasing periods of time. cDNA libraries were constructed from bulbs stored at 25 degrees Celsius (control) and...
ORGANISM(S): Lilium longiflorum 
2015-03-17 | E-MTAB-2825 | biostudies-arrayexpress
TranscriptomicsUltra-deep sequencing of plasma DNA identifies druggable mutations in hepatocellular carcinoma
The purpose of the study is to detect somatic mutations in hepatocellular carcinoma using circulating free-DNA. We used deep-sequencing data of a panel of 60 commonly mutated genes in hepatocellular carcinoma.
ORGANISM(S): Homo sapiens 
2018-04-29 | E-MTAB-5123 | biostudies-arrayexpress
TranscriptomicsGene expression profiling during adventitious root formation in carnation stem cuttings
We analysed the expression profile of genes involved in adventitious root formation in carnation cuttings in response to exogenous auxin.
ORGANISM(S): Dianthus caryophyllus 
2015-09-01 | E-MTAB-3698 | biostudies-arrayexpress
TranscriptomicsRNA-seq of mice TRAF2/Casp-8LPC-KO tumors
This model was used to study the relationship between NF-kB and PCD regulation and generated mice with combined conditional ablation of Traf2 and Caspase-8 (TRAF2/Casp-8LPC-KO) in order to block apoptosis and specifically study the role of necroptosis in Traf2-deficient hepatocytes in vivo.
ORGANISM(S): Mus musculus 
2019-05-31 | E-MTAB-4598 | biostudies-arrayexpress
TranscriptomicsGenotyping by array of copy number variation in multi-regional sampling of hepatocellular carcinoma
The purpose of the experiment is to determine purity (aberrant cell fraction), ploidy levels and copy number alterations of the samples. Several samples were taken for each of the patients. These include tumor and controls. Controls are adjacent liver tissue in most cases, and blood cells (buffy coa...
ORGANISM(S): Homo sapiens 
2020-01-16 | E-MTAB-5878 | biostudies-arrayexpress
GenomicsDeep targeted sequencing of multiregional sampling in hepatocellular carcinoma
The purpose of this experiment of high-coverage DNA sequencing of 58 frequently mutated genes in hepatocellular carcinoma (HCC) is to confirm clonal distribution of the known HCC drivers in samples corresponding to multiple regions of a tumor.
ORGANISM(S): Homo sapiens 
2020-01-16 | E-MTAB-5899 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human hepatocellular carcinoma cell line Huh7 and immortalized hepatocyte cell line THLE5B treated with experimental compound AD80, Sorafenib, and vehicle for 24 hours
To delineate the transcriptomic changes induced by AD80 relative to sorafenib, we performed RNA-sequencing (RNA-seq) on HUH7 and THLE5B cells treated for 24 hours with either DMSO, sorafenib, or AD80 near respective growth inhibitory GI50 values. HUH7 cells were plated in 6 well plates, treated for ...
ORGANISM(S): Homo sapiens 
2019-08-02 | E-MTAB-7847 | biostudies-arrayexpress
UnknownPericardial and myocardial involvement after SARS-CoV-2 infection: a cross-sectional descriptive study in healthcare workers.
Not available
S-EPMC8570413 | biostudies-literature
TranscriptomicsRNA-seq of the human HCC cell line PLC5 after 72 hours treatment with either MAGEA3 shRNA or Scramble control
To better understand the mechanism by which MAGEA3 contributes to HCC progression, we conducted RNA sequencing in the PLC5 HCC cell line after 72 hours of treatment with scramble or sh8375 in triplicate. RNA-sequencing was conducted on poly-A enriched RNA, 100 bp single reads using an Illumina HiSeq...
ORGANISM(S): Homo sapiens 
2021-05-19 | E-MTAB-8860 | biostudies-arrayexpress
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