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MetabolomicsUntargeted metabolomics reveals species-specific metabolite production and shared nutrient consumption by Pseudomonas aeruginosa and Staphylococcus aureus

While bacterial metabolism is known to impact antibiotic efficacy and virulence, the metabolic capacities of individual microbes in cystic fibrosis lung infections are difficult to disentangle from sputum samples. Here, we show that untargeted metabolomic profiling of supernatants of multiple str...

2021-05-26 | MTBLS2105 | MetaboLights
OtherLipidome of archaea From Hypersaline Lakes2
the intact polar lipids of archaea from hypersaline lakes https://doi.org/10.3389/fmicb.2019.00377 https://doi.org/10.1016/j.syapm.2022.126336
ORGANISM(S): Halococcoides Cellulosivorans Natrarchaeobius Chitinivorans Natronocalculus Amylovorans Natranaeroarchaeum Aerophilus Natrarchaeobius Haloalkaliphilus Halalkaliarchaeum Desulfuricum Natronolimnobius Sulfurireducens Natronobiforma Cellulotropha 
2022-07-07 | MSV000089832 | MassIVE
MetabolomicsGNPS Lipidome of archaea From Hypersaline Lakes2
the intact polar lipids of archaea from hypersaline lakes https://doi.org/10.3389/fmicb.2019.00377 https://doi.org/10.1016/j.syapm.2022.126336
ORGANISM(S): Halococcoides Cellulosivorans Natronocalculus Amylovorans Natrarchaeobius Chitinivorans Natranaeroarchaeum Aerophilus Halalkaliarchaeum Desulfuricum Natrarchaeobius Haloalkaliphilus Natronobiforma Cellulotropha Natronolimnobius Sulfurireducens 
2022-07-07 | MSV000089832 | GNPS
MetabolomicsGNPS Fungal extracts from Cenote Tza Itza
Untargeted metabolomics (LC/MS) of fungal extracts (chloroform:methanol) isolated from Cenote Tza Itza in Yucatan, Mexico.
ORGANISM(S): Aspergillus (ncbitaxon:5052) Cladosporium (ncbitaxon:5498) Stachybotrys (ncbitaxon:74721) 
2022-01-17 | MSV000088691 | GNPS
GenomicsIntegrative genomic profiling of hepatocellular adenomas reveals recurrent FRK activating mutations and mutational processes of malignant transformation
Hepatocellular adenomas (HCA) are benign liver tumors predominantly developed in women using oral contraception. Here, exome sequencing identified novel recurrent somatic FRK mutations that induce constitutive kinase activity, STAT3 activation and cell proliferation sensitive to Src inhibitors. We a...
EGAS00001000679 | EGA
GenomicsExome-sequencing identifies new oncogenes and tumor suppressor genes recurrently altered in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the most common primary liver malignancy. High-resolution copy number analysis of 125 tumors of which 24 were subjected to whole-exome sequencing identified 135 homozygous deletions and 994 somatic gene mutations with predicted functional consequences. We identified...
EGAS00001000217 | EGA
Genomicsexome_seq_hepatcell_adenomas - samples
Whole exome sequencing data from 30 donors (46 tumors and 30 non-tumoral whole exome sequencing, paired-end, HiSeq 2000, Illumina) collected by the Inserm U674, PI Jessica Zucman-Rossi - Institut National du Cancer (INCa), PI Fabien Calvo, France.
EGAD00001000737 | EGA
GenomicsEGAS00001001002 - samples
Description not provided
EGAD00001001096 | EGA
GenomicsEGAS00001000217 - samples
Genetic landscape of hepatocellular carcinoma
EGAD00001000131 | EGA
GenomicsExome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets
Genomic analyses promise to improve tumor characterization in order to optimize personalized treatment for patients with hepatocellular carcinoma (HCC). Exome sequencing analysis of 243 liver tumors revealed mutational signatures associated with specific risk factors, mainly combined alcohol/tobacco...
EGAS00001001002 | EGA
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