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MetabolomicsOral Engineered Microalgae- Biosystem Targeting Intestinal Villi for Irritable Bowel Syndrome
Irritable Bowel Syndrome (IBS) is a chronic gastrointestinal disorder associated with dysregulation of the gut-brain axis. Current treatment approaches often lack long-term efficacy and target specificity, and there are no drugs or formulations specifically targeting this disease. Owing to chronic a...
2025-07-18 | MTBLS12537 | MetaboLights
TranscriptomicsTranscriptomic profile of human placenta derived trophoblast organoid cultures with its tissue of origin, human placental villi.
The aim of this microarray experiment was to compare the overall transcriptomic profile of human placenta derived trophoblast organoid cultures with its tissue of origin, human placental villi. As the placental villi contains both trophoblast and stromal populations, we have included placenta derive...
ORGANISM(S): Homo sapiens 
2018-11-28 | E-MTAB-6683 | biostudies-arrayexpress
TranscriptomicsCdx2 transcription factor binding in intestinal villus and gene expression profiling in Cdx mutant mice
We conditionally inactivated mouse Cdx2, a dominant regulator of intestinal development, and mapped its genome occupancy in adult intestinal villi. Although homeotic transformation, observed in Cdx2-null embryos, was absent in mutant adults, gene expression and cell morphology were vitally compromis...
ORGANISM(S): Mus musculus 
2011-04-13 | E-GEOD-24633 | biostudies-arrayexpress
TranscriptomicsExpression data of small intestine crypts and villi from mice with nutritional and genetic risk factors for intestinal tumors
Nutritional and genetic risk factors for intestinal tumors are additive on mouse tumor phenotypes, demonstrating that diet and genetic factors impact risk by distinct combinatorial mechanisms. We analyzed expression profiles of small intestine crypts and villi from mice with nutritional and genetic ...
ORGANISM(S): Mus musculus 
2011-05-31 | E-GEOD-29538 | biostudies-arrayexpress
GenomicsThe transcription factor CDX2 maintains active enhancer in intestinal villus cells in vivo (ChIP-seq data)
We established whether partner transcription factor binding, chromatin structure, or gene expression is compromised upon loss of partner factors cdx2 or hnf4a in mouse intestinal villi. This metadata file describes the ChIP-seq componant of that data Intestinal epithelia were collected from mouse je...
ORGANISM(S): Mus musculus 
2013-02-05 | E-GEOD-34566 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human chorionic villi cells co-culutured with fetal cardiomyocytes
In the chorionic villi of placenta, trophoblasts and endothelial cells are present, and moreover mesenchymal cells (stromal cells) can be obtained. We generated cells with the mesenchymal phenotype from the chorionic mesoderm, and showed that: a) physiologically functioning cardiomyocytes were trans...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7021 | biostudies-arrayexpress
ProteomicsProteomics Study of Molecular Mechanisms Involved in Early Pregnancy Loss
To identify the proteins and molecular signaling pathways that contribute to EPL, we performed proteomics and bioinformatics analysis of the placental villi in women who have undergone EPL and in normal pregnant women.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080693 | MassIVE
GenomicsRNA-seq in Prdm16 KO doudenal and villi
RNA-seq in Prdm16 KO doudenal and villi
PRJNA573714 | ENA
TranscriptomicsWhole-transcriptome profiling analysis of first trimester placental villi in Indian women
Whole-transcriptome profiles of individual human placental villi samples from twenty-five (25) Indian women with normal pregnancies during 6- to 8-weeks of gestation were examined using human whole genome expression arrays (NimbleGen 135K). The present study focused on the whole-transcriptome profil...
ORGANISM(S): Homo sapiens 
2013-01-09 | E-GEOD-37653 | biostudies-arrayexpress
GenomicsInvestigating Human Placentation and Pregnancy Using First Trimester Chorionic Villi
Investigating Human Placentation and Pregnancy Using First Trimester Chorionic Villi
PRJNA377795 | ENA
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