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MetabolomicsOxidative phosphorylation is a metabolic vulnerability of endocrine therapy and palbociclib resistant metastatic breast cancers
Resistance to endocrine treatments and CDK4/6 inhibitors is considered a near-inevitability in most patients with estrogen receptor positive breast cancers (ER + BC). By genomic and metabolomics analyses of patients' tumours, metastasis-derived patient-derived xenografts (PDX) and isogenic cell line...
2023-06-27 | MTBLS3342 | MetaboLights
UnknownSafety and survival with GVAX pancreas prime and Listeria Monocytogenes-expressing mesothelin (CRS-207) boost vaccines for metastatic pancreatic cancer.
Not available
S-EPMC4397277 | biostudies-literature
GenomicsBreast Cancer Histology Images
Fresh frozen breast cancer H&E tissue images collected and annotated by the International Cancer Genome Consortium (ICGC), that included the BASIS collaboration. Associated with whole genome sequence data as originally described by Nik-Zainal et al, Nature, 2016 (DOI: 10.1038/nature17676) and de...
EGAD00010001911 | EGA
GenomicsFrequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
Mitochondrial genomes are separated from the nuclear genome for most of the cell cycle by the nuclear double membrane, intervening cytoplasm and the mitochondrial double membrane. Despite these physical barriers we show that somatically acquired mitochondrial-nuclear genome fusion sequences are pres...
EGAS00001001234 | EGA
GenomicsEGAS00001000165-sc-20150427 - samples
Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
EGAD00001001353 | EGA
GenomicsEGAS00001000902-sc-20150424 - samples
Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
EGAD00001001351 | EGA
GenomicsEGAS00001000160-sc-20150424 - samples
Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
EGAD00001001349 | EGA
Genomicsena-DATASET-SC-01-06-2015-15:56:18:840-199 - samples
Whole-genome bisulfite sequencing (WGBS) on 30 breast cancer cases from the BASIS project.
EGAD00001001388 | EGA
GenomicsICGC breast cancer sequencing project SNP6 data
Affymetrix SNP6.0 breast cancer genome sequencing data
EGAD00010000915 | EGA
GenomicsEGAS00001000195-sc-20150416 - samples
We propose to definitively characterise the somatic genetics of breast cancer through generation of comprehensive catalogues of somatic mutations in breast cancer cases by high coverage genome sequencing coupled with integrated transcriptomic and methylation analyses.
EGAD00001001337 | EGA
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