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MetabolomicsGut microbiota and fermentation-derived branched chain hydroxy acids mediate health benefits of yogurt consumption in obese mice
Meta-analyses suggest that yogurt consumption reduces type 2 diabetes incidence in humans, but the molecular basis of these observations remains unknown. Here we show that dietary yogurt intake preserves whole-body glucose homeostasis and prevents hepatic insulin resistance and liver steatosis in a ...
2022-02-03 | MTBLS442 | MetaboLights
UnknownThe BATTLE-2 Study: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer.
Not available
S-EPMC5065110 | biostudies-literature
TranscriptomicsIL-15 activates mTOR and primes stress-activated gene-expression leading to prolonged anti-tumor capacity of NK cells
Treatment of hematological malignancies by adoptive transfer of activated natural killer (NK) cells is limited by poor post-infusion persistence. We compared the ability of interleukin-2 (IL-2) and IL-15 to sustain human NK cell functions following cytokine withdrawal to model post-infusion performa...
ORGANISM(S): Homo sapiens 
2016-08-24 | E-GEOD-77808 | biostudies-arrayexpress
TranscriptomicsMetabolic effects of chronic dihydronicotinamide riboside (NRH) administration in mice - RNA-seq of murine tissues (NRH treatment)
NAD+ is a crucial cofactor for the activity of various enzymes, including sirtuins and ADP-ribosyl transferases, and its decline is associated with aging and metabolic-related diseases. Therefore, a strong interest has been raised in the therapeutic use of NAD+ precursors (Vitamin B3s), but many suf...
ORGANISM(S): Mus musculus 
2026-03-09 | E-MTAB-14195 | biostudies-arrayexpress
UnknownTranslational offsetting as a mode of estrogen receptor ?-dependent regulation of gene expression
Not available
S-SCDT-EMBOJ-2018-101323 | biostudies-other
GenomicsBRCA_SNV_SR - samples
single nucleotide variant calls from somatic sniper, vcf format. input for subclonal reconstruction
EGAD00001003753 | EGA
GenomicsCPCG BRCA2 - samples
Aligned sequence data from 14 Prostate cancer samples with BRCA2 mutations
EGAD00001002739 | EGA
GenomicsCPCG-BRCA-ARRAY
Raw Array data from the CPCGene BRCA study
EGAD00010001196 | EGA
GenomicsBRCA_SNV - samples
single nucleotide variant calls from somatic sniper, vcf format
EGAD00001003752 | EGA
GenomicsBRCA_SV - samples
structural variant calls from Delly, vcf format
EGAD00001003754 | EGA
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