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This project or dataset comprises raw data of the proteome of different mutant strains of M. pneumoniae (∆mpn453; ∆mpn372; CV2 (∆mpn133∆mpn372); CV0 (WT_gp35) and ∆mpn133).The proteome of the strain was used to corroborate the genotype of the obtained mutants and to discard unspected changes in the ...
ORGANISM(S): Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
2021-09-14 | PXD028011 | Pride
Mutations in the IDH1 and IDH2 genes encoding isocitrate dehydrogenases are frequent in human glioblastomas1 and cytogenetically normal acute myeloid leukemias (AML)2. These alterations are gain-of-function mutations in that they drive the synthesis of the M-bM-^@M-^\oncometaboliteM-bM-^@M-^] R-2-hy...
ORGANISM(S): Mus musculus 

OBJECTIVES: Celiac disease (CD) is a chronic enteropathy characterized by an autoimmune reaction in the small intestine of genetically susceptible individuals. The underlying causes of autoimmune reaction and its effect on host metabolism remain largely unknown. Herein, we apply ...

2020-01-22 | MTBLS729 | MetaboLights
Effects of siRNA treatment on gene expression in VCaP prostate cancer cell line
ORGANISM(S): Homo sapiens 
Microarrays were used to examine gene expression changes between bone marrow isolated haematopoeietic cell populations (LSK cells: Lin-Sca1+cKit+) populations of control and mutant (LysM-KI) mice. The LysM-KI mouse is a murine model which expresses an Idh1 (isocitrate dehydrogenase 1) mutation (I...
ORGANISM(S): Mus musculus 
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