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ProteomicsVersican regulating viscoelasticity drives pleural fibrosis via mechanotransductive signaling
Extracellular matrix (ECM) disorder was considered as the result of fibrosis, but it is recently recognized that fibrotic ECM activates a profibrotic positive feedback loop and contributes to development of fibrosis. Versican, an ECM component, participates in cell-ECM interaction and ECM regenerati...
ORGANISM(S): Homo Sapiens 
2026-01-15 | PXD073100 |
GenomicsTunable Hydrogel Viscoelasticity Modulates Human Neural Maturation
Tunable Hydrogel Viscoelasticity Modulates Human Neural Maturation
PRJNA990647 | ENA
GenomicsMatrix viscoelasticity promotes cardiac fibroblast-macrophage fibrotic crosstalk
Matrix viscoelasticity promotes cardiac fibroblast-macrophage fibrotic crosstalk
PRJNA1477827 | ENA
GenomicsExtracellular Matrix Viscoelasticity Promotes Liver Cancer Progression in Pre-Cirrhotic NASH
Extracellular Matrix Viscoelasticity Promotes Liver Cancer Progression in Pre-Cirrhotic NASH
PRJNA1026621 | ENA
GenomicsMatrix viscoelasticity regulates dendritic cell migration and immune priming [RNA-seq]
Matrix viscoelasticity regulates dendritic cell migration and immune priming [RNA-seq]
PRJNA1334380 | ENA
GenomicsMatrix viscoelasticity regulates dendritic cell migration and immune priming [ATAC-seq]
Matrix viscoelasticity regulates dendritic cell migration and immune priming [ATAC-seq]
PRJNA1334382 | ENA
TranscriptomicsExtracellular Matrix Viscoelasticity Promotes Liver Cancer Progression in Pre-Cirrhotic NASH
Type 2 diabetes mellitus (T2DM) is a major risk factor for hepatocellular carcinoma (HCC). Changes in extracellular matrix (ECM) mechanics contribute to cancer development, and increased stiffness is known to promote HCC progression in cirrhotic conditions. T2DM is characterized by an accumulation o...
ORGANISM(S): Mus musculus 
2023-10-14 | GSE245016 | GEO
GenomicsMatrix viscoelasticity regulates dendritic cell migration and immune priming [ATAC-seq]
The tumor microenvironment shapes immune surveillance through its mechanical properties, yet the role of matrix viscoelasticity remains unclear. Here, we used a collagen system with tunable viscoelasticity to define how matrix relaxation directs dendritic cell (DC) behavior. Elastic matrices impaire...
ORGANISM(S): Homo sapiens 
2026-05-13 | GSE309232 | GEO
TranscriptomicsMatrix viscoelasticity regulates dendritic cell migration and immune priming [RNA-seq]
The tumor microenvironment shapes immune surveillance through its mechanical properties, yet the role of matrix viscoelasticity remains unclear. Here, we used a collagen system with tunable viscoelasticity to define how matrix relaxation directs dendritic cell (DC) behavior. Elastic matrices impaire...
ORGANISM(S): Homo sapiens 
2026-05-13 | GSE309231 | GEO
TranscriptomicsMatrix viscoelasticity promotes cardiac fibroblast-macrophage fibrotic crosstalk
Cardiac fibrosis is driven by dynamic crosstalk between cardiac fibroblasts and macrophages, yet how tissue mechanics regulate these interactions remains poorly defined. Here, we introduce a novel viscoelastic coculture platform that enables precise interrogation of mechanical and paracrine signalin...
ORGANISM(S): Homo sapiens 
2026-09-02 | GSE335271 | GEO
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