Sort   by:  
 Page size 
MetabolomicsStress-induced enrichment of Pseudomonas sp. stimulates the adaptive response of Auxenochlorella pyrenoidosa and antibiotic-resistant proliferation

The phycosphere is an important ecological niche for bacteria and antibiotic resistance genes (ARGs). However, whether and how the interaction between microalgae and bacteria changed, and its further effect on the transmission of ARGs under pollutant stress remains enigmatic. Here, Auxenochlorell...

2025-09-26 | MTBLS11371 | MetaboLights
MetabolomicsBacillus licheniformis promotes the enrichment of Prevotella improving levels of nicotinamide in alleviating colitis

This study investigated the effects of Bacillus licheniformis supplementation on the gut metabolic profile of patients with mild-to-moderate active ulcerative colitis (UC). Patients received either mesalazine alone or mesalazine combined with Bacillus licheniformis. Fecal samples were collected a...

2026-09-11 | MTBLS15626 | MetaboLights
MetabolomicsThe murine lung microbiome is dysbalanced by the human pathogenic fungus Aspergillus fumigatus resulting in enrichment of anaerobic bacteria
Here, we report significant changes in the composition of the lung microbiome and metabolome of mice under immune suppression, infection of immunosuppressed mice with virulent and avirulent strains of the clinically important human-pathogenic fungus Aspergillus fumigatus, and treatment with the clin...
2025-07-04 | MTBLS12262 | MetaboLights
GenomicsGenome-wide Analysis of Vitamin D Receptor Binding By ChIP-Seq
We used ChIP-Seq to identify the genomic locations bound by the vitamin D receptor (VDR) in two lymphoblastoid cell lines (LCLs) (CEPH individuals GM10855 and GM10861 from the International HapMap Project) before and after calcitriol treatment for 36 hours. Immunoprecipitated DNA was sequenced using...
ORGANISM(S): Homo sapiens 
2010-06-22 | E-GEOD-22484 | biostudies-arrayexpress
MetabolomicsNicotinamide Riboside is Uniquely Bioavailable in People and Mice
Nicotinamide riboside (NR) is in wide use as an NAD+ precursor vitamin. Here we conducted experiments to determine the time and dose-dependent effects of NR on blood, liver and heart NAD+ metabolism in people and mice. We report that human blood cell NAD+ can rise as much as 2.7-fold with a single d...
2016-09-09 | MTBLS368 | MetaboLights
TranscriptomicsTranscription profiling of mouse liver from wild type and Wrn mutant animals with or without vitamin C treatment
Werner syndrome (WS) is a rare disorder characterized by the premature onset of a number of age-related diseases. The gene responsible for WS is believed to be involved in different aspects of transcription, replication, and/or DNA repair. We generated a mouse model with a deletion in the helicase d...
ORGANISM(S): Mus musculus 
2009-09-11 | E-GEOD-14549 | biostudies-arrayexpress
ProteomicsProteomic Analysis Reveals the Mechanisms Underlying Ischemic Stroke Induced by Vitamin B12 Deficiency
Recruit patients with first-ever acute ischemic stroke (AIS) and classify them into two study groups based on the presence or absence of vitamin B12 deficiency, while also including a matched healthy control group. Utilize 4D-DIA proteomics technology to analyze the protein expression profiles and i...
ORGANISM(S): Homo sapiens (Human) 
2026-02-20 | PXD062264 | Pride
Vitamin b12 deficiency Proteomic Ischemic stroke 
ProteomicsVitamin C alters the amount of specific endoplasmic reticulum associated proteins involved in lipid metabolism in the liver of mice synthesizing a nonfunctional WRN mutant protein
Werner syndrome (WS) is a premature aging disorder caused by mutations in a DNA helicase/exonuclease. Mice lacking the helicase domain of the Wrn protein orthologue exhibit transcriptomic and metabolic alterations, some of which are reversed by vitamin C. Recent studies on the liver of these animals...
ORGANISM(S): Mus musculus (Mouse) 
2018-03-02 | PXD007758 | Pride
Mouse model Liver proteome Lc-msms shotgun Vitamin c Endoplasmic reticulum Werner syndrome Label free quantification 
GenomicsTranscriptomics identifies blunted immunomodulatory effects of vitamin D in people with multiple sclerosis
Vitamin D deficiency is a risk factor for developing multiple sclerosis (MS). However, the immune effects of vitamin D in people with MS are not well understood. We analyzed transcriptomic datasets generated by RNA sequencing of immune cell subsets (CD4+, CD8+ T cells, B cells, monocytes) from 33 he...
EGAS00001007254 | EGA
GenomicsMixed community enrichment culture
Phage-based microbiome manipulation elucidates vitamin exchange interactions within a community context
PRJNA1254232 | ENA
Sort   by:  
 Page size