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TranscriptomicsTruncation of LOC100288798 (SLC38A4-AS) lncRNA in human haploid KBM7 cell line
Many thousand long non-coding (lnc) RNAs are mapped in the human genome. Time consuming studies using reverse genetic approaches by post-transcriptional knock-down or genetic modification of the locus demonstrated diverse biological functions for a few of these transcripts. The Human Gene Trap Mutan...
ORGANISM(S): Homo sapiens 
2015-12-22 | E-GEOD-71284 | biostudies-arrayexpress
TranscriptomicsThe hypoxia marker pimonidazole reflects a transcriptional program associated with aggressive prostate cancer.
We aimed to investigate the transcriptional program associated with pimonidazole staining in prostate cancer. A pimonidazole gene signature was identified that showed positive correlation to Ki67 labeling index, indicating increased proliferation in pimonidazole positive tumors. A positive correlati...
ORGANISM(S): Homo sapiens 
2015-01-05 | E-GEOD-55935 | biostudies-arrayexpress
TranscriptomicsHypoxia-independent downregulation of hypoxia inducible factor 1 targets by androgen deprivation therapy in prostate cancer.
Hypoxia inducible factor 1 (HIF1) has been shown to cooperate with the androgen receptor (AR) in activation of oncogenic pathways in prostate cancer (PCa). Here we hypothesized that HIF1 also plays a role in PCa response to androgen deprivation therapy (ADT). Comparison of gene expression profiles o...
ORGANISM(S): Homo sapiens 
2013-10-02 | E-GEOD-42868 | biostudies-arrayexpress
UnknownHypoxic tumor kinase signaling mediated by STAT5A in development of castration-resistant prostate cancer.
Not available
S-EPMC3651196 | biostudies-literature
UnknownLocalization of primary prostate cancer: FACBC PET/CT compared with multiparametric MRI using histopathology as reference standard.
Not available
S-EPMC8569330 | biostudies-literature
UnknownPhase I/IIa clinical trial of a novel hTERT peptide vaccine in men with metastatic hormone-naive prostate cancer.
Not available
S-EPMC11028648 | biostudies-literature
UnknownThe role of glycogen synthase kinase 3 (GSK3) in cancer with emphasis on ovarian cancer development and progression: A comprehensive review.
Not available
S-EPMC7861620 | biostudies-literature
UnknownAmino acid transporter expression and 18F-FACBC uptake at PET in primary prostate cancer.
Not available
S-EPMC8414398 | biostudies-literature
UnknownThe tumour hypoxia marker pimonidazole reflects a transcriptional programme associated with aggressive prostate cancer.
Not available
S-EPMC4453458 | biostudies-literature
UnknownA prognostic hypoxia gene signature with low heterogeneity within the dominant tumour lesion in prostate cancer patients.
Not available
S-EPMC9296675 | biostudies-literature
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