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TranscriptomicsDeep-sequencing of endogenous microRNAs from human endothelial cells exposed to hypoxia and normoxia
Human Umbelical Vein Endothelial Cells (HUVEC) were cultured in vitro and exposed to 1% oxygen or normoxia for 24 hours. Then, small RNA libraries were prepared and sequenced using sequencing-by-ligation technique (Solid3 Plus Sequencer platform). Alignment versus miRBase v14.0 identified >400 diffe...
ORGANISM(S): Homo sapiens 
2012-02-07 | E-GEOD-26497 | biostudies-arrayexpress
TranscriptomicsImplication of Long noncoding RNAs in the endothelial cell response to hypoxia II.
Long noncoding RNAs (lncRNAs) are non-protein coding RNAs regulating gene expression. Although for some lncRNAs a relevant role in hypoxic endothelium has been shown, the regulation and function of lncRNAs is still largely unknown in the vascular physio-pathology. Taking advantage of next-generation...
ORGANISM(S): Homo sapiens 
2016-08-25 | E-GEOD-76739 | biostudies-arrayexpress
TranscriptomicsEffect of neurotrophin receptor p75 (p75NTR) over-expression on the miRNAome of human umbilical vein endothelial cells
MicroRNAs (miRNAs) are small non-protein-coding RNAs that are incorporated into the RNA-induced silencing complex (RISC) and inhibit gene expression by regulating the stability and/or the translational efficiency of target mRNAs. p75NTR, which is scarcely present in healthy endothelial cells (ECs), ...
ORGANISM(S): Homo sapiens 
2014-01-11 | E-GEOD-53899 | biostudies-arrayexpress
TranscriptomicsImplication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing.
Long noncoding RNAs (lncRNAs) are non-protein coding RNAs regulating gene expression. Although for some lncRNAs a relevant role in hypoxic endothelium has been shown, the regulation and function of lncRNAs is still largely unknown in the vascular physio-pathology. Taking advantage of next-generation...
ORGANISM(S): Homo sapiens 
2016-08-25 | E-GEOD-76743 | biostudies-arrayexpress
TranscriptomicsImplication of Long noncoding RNAs in the endothelial cell response to hypoxia I.
Long noncoding RNAs (lncRNAs) are non-protein coding RNAs regulating gene expression. Although for some lncRNAs a relevant role in hypoxic endothelium has been shown, the regulation and function of lncRNAs is still largely unknown in the vascular physio-pathology. Taking advantage of next-generation...
ORGANISM(S): Homo sapiens 
2016-08-25 | E-GEOD-76741 | biostudies-arrayexpress
TranscriptomicsEffect of mir-210 over-expression on the miRNAome of human umbilical vein endothelial cells
MicroRNAs (miRNAs) are small non-protein-coding RNAs that are incorporated into the RNA-induced silencing complex (RISC) and inhibit gene expression by regulating the stability and/or the translational efficiency of target mRNAs. miR-210 can be considered a master miRNA of hypoxic response and is cu...
ORGANISM(S): Homo sapiens 
2015-01-01 | E-GEOD-35365 | biostudies-arrayexpress
UnknownThe expression of the BPIFB4 and CXCR4 associates with sustained health in long-living individuals from Cilento-Italy.
Not available
S-EPMC5361669 | biostudies-literature
UnknownROD1 is a seedless target gene of hypoxia-induced miR-210.
Not available
S-EPMC3443109 | biostudies-literature
UnknownHypoxia-Induced miR-210 Is Necessary for Vascular Regeneration upon Acute Limb Ischemia.
Not available
S-EPMC6981725 | biostudies-literature
UnknownmiR-210 overexpression increases pressure overload-induced cardiac fibrosis.
Not available
S-EPMC11874870 | biostudies-literature
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