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ProteomicsUnraveling the Bombus terrestris hemolymph, a readout of the immune response to microbial infections, through complementary mass spectrometry approaches
Pollinators are of crucial importance for maintaining biodiversity in ecosystems and for agriculture, including the Buff-tailed bumblebee Bombus terrestris. The health decline in these populations is thought to be linked to various abiotic and biotic stressors. In the hope of protecting these popula...
ORGANISM(S): Bombus terrestris (Buff-tailed bumblebee) (Apis terrestris) 
2023-05-10 | PXD035224 | Pride
Proteomics Response to pathogens Immune response Bumblebee Bee health Molecular fingerprints Pollinators Bacterial infections 
ProteomicsImpact of an antifungal insect defensin on the proteome of the phytopathogenic fungus Botrytis cinerea
ETD151, an analogue of the antifungal insect defensin heliomicin, is an antifungal peptide active against yeasts and filamentous fungi. In order to decipher the mechanisms underlying its molecular action on the phytopathogenic fungus Botrytis cinerea, a necrotrophic pathogen responsible for gray mol...
ORGANISM(S): Botryotinia fuckeliana (Noble rot fungus) (Botrytis cinerea) 
2020-01-29 | PXD016740 | Pride
Insect defensin Botrytis cinerea Proteomics Heliomicin Mechanism of action Fungal infection Antifungal defensin 
ProteomicsInsights into the natural defences of a coral reef fish against gill ectoparasites: integrated metabolome and microbiome approach.
Understanding natural defence mechanisms against parasites can be a valuable tool for the development of innovative therapies. In this study, we investigated the interplay between the gill mucus metabolome and microbiome of Chaetodon lunulatus, a butterflyfish known to avoid gill monogeneans whilst ...
ORGANISM(S): Chaetodon lunulatus 
2020-11-25 | PXD018867 | Pride
Chaetodon Multi-omics Fish mucus Metabolomics Microbiome Host-parasite interactions Butterflyfish 
ProteomicsDissecting the molecular mechanisms of mother-to-egg immune protection in the mealworm beetle Tenebrio molitor
In a number of species, individuals exposed to pathogens can mount an immune response and transmit this immunological experience to their offspring, thereby protecting them against persistent threats. Such vertical transfer of immunity, named trans-generational immune priming (TGIP), has been descri...
ORGANISM(S): Tenebrio molitor 
2020-10-08 | PXD018772 | Pride
Trans-generational immune priming  invertebrate immunity  host-pathogens interaction  molecular mechanisms  omics  antimicrobial peptides 
ProteomicsProteomics of anatomical sections of the gut of Nosema-infected Western honey bee (Apis mellifera) reveals different early responses to Nosema spp. isolates
We aim to evaluate the effects of four Nosema spores’ isolates, (i) and (ii) N. ceranae isolated from A. mellifera hosts from two different geographical origins, (iii) N. ceranae from A. cerana host and (iv) N. apis from A. mellifera, on the A. mellifera on gut proteomics at the early stage of infec...
ORGANISM(S): Nosema ceranae Nosema apis Apis mellifera (Honeybee) 
2020-11-25 | PXD021848 | Pride
Apis mellifera Proteomics Digestive tract Nosema ceranae Nosema apis 
ProteomicsHaemoproteomics of Bombus terrestris following pesticide exposure and interaction with Crithidia bombi
Pesticides pose a potential threat to bee health, especially in combination with other stressors, like parasites. However, pesticide risk assessment tests them in isolation from other stresses. We tested acute oral doses of three pesticides - glyphosate, Amistar and sulfoxaflor - on the bumblebee, B...
ORGANISM(S): Bombus terrestris terrestris Crithidia bombi 
2023-02-09 | PXD039916 | Pride
Bumble bee  immune response  maldi beetyping  differential proteomics 
ProteomicsCuticular structure proteomics analyses of the pea aphid Acyrthosiphon pisum
Aphids are sap-feeding insects with piercing-sucking mouthparts. They are serious pests in agriculture and provoke significant losses, with a formidable capacity to transmit numerous plant viruses causing diseases in almost all important crops. The majority of viruses are acquired after feeding on a...
ORGANISM(S): Acyrthosiphon pisum (Pea aphid) 
2020-01-29 | PXD016517 | Pride
Immunolabeling Proteomics Acrostyle Aphid stylets Virus receptor Cuticular structure 
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