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ProteomicsZMYND10 functions in a chaperone-relay during axonemal dynein assembly
Molecular chaperones are abundant cellular proteins that promote the folding, function and macromolecular assembly of a diverse set of substrate proteins, also known as clients. Regulation of chaperone specificity and function involves association with a growing set of distinct cofactors, or cochape...
ORGANISM(S): Mus musculus (Mouse) 
2018-07-12 | PXD006849 | Pride
Primary ciliary dyskinesia 
ProteomicsPharmacological inhibition of the glucocorticoid regenerating enzyme 11ßhydroxysteroid dehydrogenase type 1 after myocardial infarction preserves cardiac function in a translational pig model
Background and Purpose: Adrenal glucocorticoids (GC) increase acutely after myocardial infarction (MI) and thereafter tissue levels are maintained selectively within cells expressing the enzyme 11ßHydroxysteroid Dehydrogenase type 1 (11ßHSD1) that regenerates active GC from circulating metabolites. ...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2026-01-15 | PXD055401 | Pride
Heart Pig 
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