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TranscriptomicsChromatin immunopreciptiation of human breast epithelial HME1 cell lines over-expressing wild type or mutant p53 to study acetylation of histone H4
acetylation of histone H4 was studied using ChIP on chip technique in breast epithelial HME1 cell lines overexpressing wt or mutant p53
ORGANISM(S): Homo sapiens 
2008-10-25 | E-MEXP-1494 | biostudies-arrayexpress
TranscriptomicsChromatin immunopreciptiation of human breast epithelial HME1 cell lines over-expressing wild type or mutant p53 to study acetylation of histone H3
acetylation of histone H3 was studied using ChIP on chip technique in breast epithelial HME1 cell lines overexpressing wt or mutant p53
ORGANISM(S): Homo sapiens 
2008-10-25 | E-MEXP-1493 | biostudies-arrayexpress
TranscriptomicsChromatin immunopreciptiation of human breast epithelial HME1 cell lines over-expressing wild type or mutant p53 to study p53 binding
p53 binding was studied using ChIP on chip technique in breast epithelial HME1 cell lines overexpressing wt or mutant p53
ORGANISM(S): Homo sapiens 
2008-10-25 | E-MEXP-1491 | biostudies-arrayexpress
TranscriptomicsHistone H3 acetylation of miRNA genes in HMEC and HMF
Normal cell type specific histone H3 acetylation of miRNA genes. HMEC and HMF represent two distinct differentiated cell type present in mammary gland each with a distinct phenotype, a distinct epigenotype as well as distinct miRNA expression pattern. The aim of the study was to determine how epigen...
ORGANISM(S): Homo sapiens 
2011-04-05 | E-GEOD-28375 | biostudies-arrayexpress
TranscriptomicsEfficient immortalization of normal human mammary epithelial cells using two pathologically relevant agents does not require gross genomic alterations
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-07-03 | E-GEOD-48504 | biostudies-arrayexpress
TranscriptomicsmiRNA genes in HMEC and HMF
This SuperSeries is composed of the following subset Series: GSE28374: DNA methylation of miRNA genes in HMEC and HMF GSE28375: Histone H3 acetylation of miRNA genes in HMEC and HMF GSE28376: Histone H3 lysine 27 trimethylation of miRNA genes in HMEC and HMF GSE28377: Histone H3 lysine 4 trimethylat...
ORGANISM(S): Homo sapiens 
2011-04-05 | E-GEOD-28380 | biostudies-arrayexpress
TranscriptomicsPatterns of aberrant DNA methylation after toxicant-induced malignant transformation (MeDIP-chip dataset 1)
Aberrant DNA methylation is frequently observed in cancer. The aim of this study was to determine how DNA methylation is changed after toxicant-induced malignant transformation. This study also puts the DNA methylation changes into context with respect to the aberrant DNA methylation events that occ...
ORGANISM(S): Homo sapiens 
2012-06-25 | E-GEOD-38926 | biostudies-arrayexpress
TranscriptomicsPatterns of aberrant DNA methylation after toxicant-induced malignant transformation (MeDIP-chip dataset 2)
Aberrant DNA methylation is frequently observed in cancer. The aim of this study was to determine how DNA methylation is changed after toxicant-induced malignant transformation. This study also puts the DNA methylation changes into context with respect to the aberrant DNA methylation events that occ...
ORGANISM(S): Homo sapiens 
2012-06-25 | E-GEOD-38928 | biostudies-arrayexpress
TranscriptomicsAberrant DNA methylation of miRNA genes in breast cancer
Aberrant DNA methylation is frequently observed in cancer. The aim of the study was to determine how is DNA methylation of miRNA genes changed in breast cancer cell lines an breast tumor specimens. Breast cancer cell lines vs. HMEC. Breast tumor tissue specimens vs. non-tumor tissue specimens. Biol...
ORGANISM(S): Homo sapiens 
2012-05-25 | E-GEOD-38254 | biostudies-arrayexpress
TranscriptomicsDNA methylation of mortal and immortal breast cells
DNA methylation changes during immortalization of breast cells. The aim of the study was to determine whether differential epigentic state of TERT gene is involved in immortalization of breast cells. comparison of Pre-Stasis, Post-Selection, and immortal cells
ORGANISM(S): Homo sapiens 
2013-07-03 | E-GEOD-48447 | biostudies-arrayexpress
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