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TranscriptomicsPolypyrimidine tract-binding protein homologues from Arabidopsis are key regulators of alternative splicing with implications in fundamental developmental processes
Alternative splicing (AS) generates transcript variants by the definition of different exonic and intronic regions and causes a massive expansion of transcriptome diversity. Changes in AS patterns have been found to be linked to manifold biological processes, yet fundamental aspects such as the regu...
ORGANISM(S): Arabidopsis thaliana 
2012-10-22 | E-GEOD-41433 | biostudies-arrayexpress
TranscriptomicsPhotomorphogenesis of Arabidopsis seedlings is accompanied by complex alternative splicing alterations
We analyzed transcriptome-wide gene expression and AS changes in etiolated Arabidopsis seedlings exposed to red, blue, and white light. Our study revealed that different types of light signals trigger rapid AS responses of numerous genes, including splicing factors and other functional groups. Among...
ORGANISM(S): Arabidopsis thaliana 
2016-10-23 | E-GEOD-70575 | biostudies-arrayexpress
TranscriptomicsNonsense-mediated decay of alternative precursor mRNA splicing variants is a major determinant of the eukaryotic steady state transcriptome
Nonsense-mediated mRNA decay (NMD) is a eukaryotic surveillance pathway that recognizes aberrant transcripts arising from mutations and transcriptional mistakes. Moreover, differential transcript processing such as alternative precursor mRNA splicing (AS) can generate NMD substrates, however, the ex...
ORGANISM(S): Arabidopsis thaliana 
2013-10-01 | E-GEOD-41432 | biostudies-arrayexpress
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