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TranscriptomicsMicroRNA regulate immune pathways in T-cells in multiple sclerosis (MS) mRNA
MicroRNAs are small noncoding RNA molecules that are involved in the control of gene expression. To investigate the role of microRNA in multiple sclerosis (MS), we performed global microarray analyses of mRNA and microRNA in peripheral blood T-cells from relapsing-remitting MS patients and controls....
ORGANISM(S): Homo sapiens 
2013-08-02 | E-GEOD-43591 | biostudies-arrayexpress
TranscriptomicsMicroRNA regulate immune pathways in T-cells in multiple sclerosis (MS) miRNA
MicroRNAs are small noncoding RNA molecules that are involved in the control of gene expression. To investigate the role of microRNA in multiple sclerosis (MS), we performed global microarray analyses of mRNA and microRNA in peripheral blood T-cells from relapsing-remitting MS patients and controls....
ORGANISM(S): Homo sapiens 
2013-08-02 | E-GEOD-43590 | biostudies-arrayexpress
TranscriptomicsDifferences in gene expression and cytokines levels between newly diagnosed and chronic pediatric immune thrombocytopenia (ITP)
Immune thrombocytopenia (ITP) is an autoimmune disease where platelets are destroyed prematurely. In the majority of children the disease resolves but in some it becomes chronic. To investigate whether the two forms of the disease are similar or separate entities we performed DNA microarray analysis...
ORGANISM(S): Homo sapiens 
2013-08-05 | E-GEOD-46922 | biostudies-arrayexpress
TranscriptomicsMicroRNA regulate immunological pathways in T-cells in immune thrombocytopenia (ITP) [miRNA]
MicroRNA are small non-coding RNA molecules that regulate gene expression. To investigate the role of microRNA in ITP, we performed genome-wide expression analyses of mRNA and microRNA in T-cells from ITP patients and controls. We identified 1,915 regulated genes and 22 regulated microRNA that diffe...
ORGANISM(S): Homo sapiens 
2013-01-22 | E-GEOD-43178 | biostudies-arrayexpress
TranscriptomicsMolecular basis for remission and tolerance induction in pediatric ITP
Children with newly diagnosed ITP that after 12 month enter remission, shows molecular separate entities. The molecular basis for remission and tolerance induction is characterized by gene transcriptional profiling Global gene expression profile in isolated T-cells from 6 children with newly diagnos...
ORGANISM(S): Homo sapiens 
2016-02-06 | E-GEOD-56232 | biostudies-arrayexpress
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