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MetabolomicsMetabolic responses of rice cultivars with different tolerance to combined heat and drought stress under field conditions
Rice is susceptible to both heat and drought stress, in particular during flowering and grain filling, when both grain yield and quality may be severely compromised. However, under field conditions, these two stresses rarely occur separately. Under well-watered conditions, plants avoid heat stress b...
2019-04-25 | MTBLS801 | MetaboLights
TranscriptomicsKlf4
Klf4 is the zinc finger transcription factor indispensable for terminal maturation of epithelial tissues and part of group of proteins for the generation of pluripotent embryonic stem cells from differentiated tissues. No definitive in-vivo-function of Klf4 in the hematopoietic system has been estab...
ORGANISM(S): Mus musculus 
2012-07-30 | E-GEOD-11572 | biostudies-arrayexpress
UnknownKinetics of oxytocin effects on amygdala and striatal reactivity vary between women and men.
Not available
S-EPMC7235226 | biostudies-literature
TranscriptomicsAIR100 SysBio Approach
Organotypic culture of human primary bronchial epithelial cells is a useful in vitro system to study normal biological processes and lung disease mechanisms, to develop new therapies, and to assess the biological perturbations induced by environmental pollutants. Herein, we further develop this in v...
ORGANISM(S): Homo sapiens 
2012-04-01 | E-MTAB-877 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human mesenchymal stromal cells to reveal senescence associated gene expression changes
Transcription profiling of human mesenchymal cells (MSCs) after ex vivo expansion under culture conditions supporting extensive cell proliferation. Highly efficient cell expansion within short time (~40 days) and comparison of gene expression profiles from MSCs after primary seeding, defined as earl...
ORGANISM(S): Homo sapiens 
2009-12-31 | E-MEXP-1997 | biostudies-arrayexpress
TranscriptomicsANGUSTIFOLIA 3 binds SWI/SNF chromatin remodeling complexes to regulate transcription during Arabidopsis leaf development
The transcriptional coactivator ANGUSTIFOLIA 3 (AN3) stimulates cell proliferation during Arabidopsis leaf development, but the molecular mechanism is largely unknown. We show here that inducible nuclear localization of AN3 during initial leaf growth results in differential expression of important t...
ORGANISM(S): Arabidopsis thaliana 
2014-09-09 | E-GEOD-42875 | biostudies-arrayexpress
MetabolomicsATF6 activation alters colonic lipid metabolism causing tumor-associated microbial adaptation

The induction of endoplasmic reticulum unfolded protein responses (UPRER) contributes to cancer development and progression. We recently linked microbiota-related triggers to the tumor-promoting role of signal transducer activating transcription factor 6 (ATF6) in the colon. Here we substantiate ...

2025-07-02 | MTBLS7387 | MetaboLights
TranscriptomicsAIR100 SysBio Approach
Organotypic culture of human primary bronchial epithelial cells is a useful in vitro system to study normal biological processes and lung disease mechanisms, to develop new therapies, and to assess the biological perturbations induced by environmental pollutants. Herein, we further develop this in v...
ORGANISM(S): Homo sapiens 
2012-04-01 | E-MTAB-874 | biostudies-arrayexpress
TranscriptomicsHuman bone and marrow niche formation by mesenchymal progenitors in vivo is predefined by an organotypic epigenetic signature
In this study, we have analyzed DNA methylation characteristics of human mesenchymal stem and progenitor cells (MSPCs) form different tissue sources including bone marrow (BM), white adipose tissue (WAT ), umbilical cord (UC) as well as dermal fibroblasts by using the HumanMethylation450K array. Cel...
ORGANISM(S): Homo sapiens 
2015-02-04 | E-GEOD-41933 | biostudies-arrayexpress
ProteomicsMetrologically traceable quantification of three apolipoprotein E isoforms in cerebrospinal fluid
Apolipoprotein E (apoE) is a 317-amino-acid long glycoprotein with three common isoforms (apoE2, apoE3, and apoE4) encoded by three apoE alleles (ε2, ε3, and ε4). These polymorphic forms arise from single amino acid substitutions with Cys and Arg interchanged at positions 112 and 158 (mature protein...
ORGANISM(S): Homo Sapiens 
2023-06-13 | PXD038803 | panorama
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