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TranscriptomicsDNA methylation profiles of freshly isolated CD34+ cells and upon expansion on either tissue culture plastic (TCP) or mesenchymal stromal cells (MSCs)
Hematopoietic stem and progenitor cells (HPCs) can be maintained in vitro, but the vast majority of their progeny loses M-bM-^@M-^\stemnessM-bM-^@M-^] during culture. In this study, we have analyzed DNA methylation (DNAm) profiles of freshly isolated CD34+ cells and upon expansion on either tissue c...
ORGANISM(S): Homo sapiens 
2013-12-03 | E-GEOD-40799 | biostudies-arrayexpress
TranscriptomicsIn vitro Expansion of Hematopoietic Stem Induces Gene Expression Changes
Hematopoietic stem and progenitor cells (HPCs) can be maintained in vitro, but the vast majority of their progeny loses M-bM-^@M-^\stemnessM-bM-^@M-^] during culture. We have analyzed DNA methylation (DNAm) profiles of freshly isolated CD34+ cells and upon expansion on either tissue culture plastic ...
ORGANISM(S): Homo sapiens 
2013-12-03 | E-GEOD-40669 | biostudies-arrayexpress
TranscriptomicsLong-term culture associated gene expression changes in MSC (TGFb treatment)
Mesenchymal stromal cells (MSC) were isolated from human bone marrow. Here, we have compared gene expression profiles of MSC at early and late passages and upon stimulation with transforming growth factor beta 1 (TGF-b1). Stimulation was performed with 1ng/mL TGF-b1 for 1, 4, or 12 hours as indicate...
ORGANISM(S): Homo sapiens 
2014-02-05 | E-GEOD-46019 | biostudies-arrayexpress
UnknownMicroRNA expression profiles of serum from patients before and after chemotherapy.
Not available
S-EPMC4664708 | biostudies-literature
UnknownSerum of myeloproliferative neoplasms stimulates hematopoietic stem and progenitor cells.
Not available
S-EPMC5979002 | biostudies-literature
UnknownA Novel Homozygous KLHL3 Mutation as a Cause of Autosomal Recessive Pseudohypoaldosteronism Type II Diagnosed Late in Life.
Not available
S-EPMC9393831 | biostudies-literature
UnknownHematopoietic stem and progenitor cells acquire distinct DNA-hypermethylation during in vitro culture.
Not available
S-EPMC3842544 | biostudies-literature
UnknownFeedback signals in myelodysplastic syndromes: increased self-renewal of the malignant clone suppresses normal hematopoiesis.
Not available
S-EPMC3998886 | biostudies-literature
UnknownSerum after autologous transplantation stimulates proliferation and expansion of human hematopoietic progenitor cells.
Not available
S-EPMC3060918 | biostudies-literature
UnknownMicroRNAs and Metabolites in Serum Change after Chemotherapy: Impact on Hematopoietic Stem and Progenitor Cells.
Not available
S-EPMC4449031 | biostudies-literature
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