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TranscriptomicsAccumulation of noncoding RNA due to an RNase P defect in Saccharomyces cerevisiae
To investigate the possible range of additional RNase P substrates in vivo a strand-specific, high-density microarray was used to analyze what RNA accumulates with a mutation in the catalytic RNA subunit of nuclear RNase P in Saccharomyces cerevisiae. A wide variety of noncoding RNAs were shown to a...
ORGANISM(S): Saccharomyces cerevisiae 
2011-08-29 | E-MEXP-3140 | biostudies-arrayexpress
TranscriptomicsIdentification of RNAs that are physically and functionally associated with RNase P
Numerous RNAs copurify with RNase P and are affected by temperture sensitive mutations in conserved residues with the essential RNA and protein subunits. Specifically, RNase P physically interacts with ribosomal protein mRNAS and the intron-encoded box C/D snoRNAs. Keywords: RNA copurification, tem...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-01 | E-GEOD-10514 | biostudies-arrayexpress
UnknownA Conserved Structural Role for the Walker-A Lysine in P-Loop Containing Kinases.
Not available
S-EPMC8517177 | biostudies-literature
TranscriptomicsDifferentially expressed genes analysis between Eupolyphaga sinensis Walker (ESW) and Taspine derivate
To gain insights into the mechanisms of Eupolyphaga sinensis Walker (ESW) and taspine derivate on inhibition to HCC, we have employed whole genome microarray expression profiling as a discovery platform to identify different genes between ESW-treated sample and control. At the same time, the differe...
ORGANISM(S): Homo sapiens 
2013-11-21 | E-GEOD-52554 | biostudies-arrayexpress
UnknownRole of highly central residues of P-loop and it's flanking region in preserving the archetypal conformation of Walker A motif of diverse P-loop NTPases.
Not available
S-EPMC3563412 | biostudies-literature
TranscriptomicsNLRC5 is a transcriptional regulator of MHC class I genes
NLRC5 is a member of the NLR family of proteins. The observation that NLRC5 is found in the nucleus prompted us to perform a gene array to identify putative target genes of NLRC5. We generated Jurkat T cell lines that stably express either the wild-type or mutant forms of NLRC5 harboring mutations i...
ORGANISM(S): Homo sapiens 
2010-07-30 | E-GEOD-22064 | biostudies-arrayexpress
TranscriptomicsClone History Shapes Populus Drought Responses
Just as animal monozygotic twins can experience different environmental conditions by being reared apart, individual genetically-identical trees of the genus Populus can also be exposed to contrasting environmental conditions by being grown in different locations. As such, clonally-propagated Popul...
ORGANISM(S): Populus hybrid sp. 'Walker' 
2011-05-01 | E-GEOD-27693 | biostudies-arrayexpress
UnknownThe complete mitochondrial genome of West Indian drywood termite, Cryptotermes brevis (Walker) (Isoptera: Kalotermitidae).
Not available
S-EPMC7687630 | biostudies-literature
UnknownAn interparticle relatively motional DNA walker and its sensing application.
Not available
S-EPMC8159414 | biostudies-literature
UnknownConserved Walker A cysteines 431 and 1074 in human P-glycoprotein are accessible to thiol-specific agents in the apo and ADP-vanadate trapped conformations.
Not available
S-EPMC3850068 | biostudies-literature
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