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TranscriptomicsTranscription profiling of Drosophila body wall and wing/hinge fragments from wing imaginal discs to identify genes with localized expression patterns
Wing imaginal discs were dissected to generate body wall and wing/hinge fragments. Targets from three biological replicates of each were generated and the expression profiles were determined using Affymetrix Drosophila Genechip 1 arrays. Comparisons between the sample groups allow the identificati...
ORGANISM(S): Drosophila melanogaster 
2007-07-06 | E-GEOD-93 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wild type, mur4 knock-out and prl1 knock-out Arabidopsis plants grown in media with 1% glucose
Sugars such as glucose function as signal molecules that regulate gene expression, growth and development in plants, animals and yeast. To understand the molecular mechanisms of sugar responses, we isolated and characterized an Arabidopsis thaliana mutant, high sugar- response 8 (hsr8), which enhanc...
ORGANISM(S): Arabidopsis thaliana 
2007-08-10 | E-NASC-78 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse brain from animals treated with cocaine vs controls
Several recent reports show that the cerebral cortex in humans and animals with altered expressions of Wnt/cadherin network-associate molecules display cytoarchitectural abnormalities reminiscent of cortical dysplasias seen in some (mouse-, rat-, and monkey-based) animal models of prenatal cocaine e...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-6628 | biostudies-arrayexpress
TranscriptomicsAn antibiotic that inhibits a late step in wall teichoic acid biosynthesis induces the cell wall stress stimulon in Staphylococcus aureus
Wall teichoic acids (WTAs) are phosphate-rich, sugar-based polymers attached to the cell walls of most Gram-positive bacteria. In Staphylococcus aureus, these anionic polymers regulate cell division, protect cells from osmotic stress, mediate host colonization, and mask enzymatically susceptible pep...
ORGANISM(S): Staphylococcus aureus 
2012-01-12 | E-GEOD-34441 | biostudies-arrayexpress
TranscriptomicsCell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2
The cell wall is essential for viability of fungi and is an effective drug target in pathogens such as Candida albicans. The contribution of posttranscriptional gene regulators to cell wall integrity in C. albicans is unknown. We show that the C. albicans Ccr4-Pop2 mRNA deadenylase, a regulator of m...
ORGANISM(S): Candida albicans 
2010-12-10 | E-GEOD-25891 | biostudies-arrayexpress
TranscriptomicsTranscriptional profile comparison of M. tuberculosis PDIM spontaneous mutants
Transcriptional profile comparison among PDIM positive and negative isolates. Standard in vitro exponential phase cultures of M. tuberculosis H37Rv ATCC27294 were plated on 7H11 plates. Individual colonies were sub-cultured in 7H9 broth and metabolically labeled with [14C] propionic acid. The apolar...
ORGANISM(S): Mycobacterium tuberculosis 
2010-05-16 | E-GEOD-17234 | biostudies-arrayexpress
TranscriptomicsGenomic comparison of M. tuberculosis PDIM spontaneous mutants
Genomic comparisons among PDIM positive and negative isolates. Standard in vitro exponential phase cultures of M. tuberculosis H37Rv ATCC27294 were plated on 7H11 plates. Individual colonies were sub-cultured in 7H9 broth and metabolically labeled with [14C] propionic acid. The apolar lipid fraction...
ORGANISM(S): Mycobacterium tuberculosis 
2010-05-16 | E-GEOD-17232 | biostudies-arrayexpress
TranscriptomicsDaptomycin-Resistance Mechanisms in Clinically-Derived Staphylococcus aureus Strains Assessed by a Combined Transcriptomics and Proteomics Approach
Objectives: Development of daptomycin resistance (DAPR) in Staphylococcus aureus is associated with clinical treatment failures. Mechanism(s) of such resistance has not been clearly defined. Methods: We studied an isogenic daptomycin-susceptible (DAPS) and daptomycin-resistant (DAPR) S. aureus stra...
ORGANISM(S): Staphylococcus aureus 
2011-12-02 | E-GEOD-28632 | biostudies-arrayexpress
UnknownThe monothiol glutaredoxin Grx4 influences thermotolerance, cell wall integrity, and Mpk1 signaling in Cryptococcus neoformans.
Not available
S-EPMC8527476 | biostudies-literature
UnknownOff the wall: The rhyme and reason of Neurospora crassa hyphal morphogenesis.
Not available
S-EPMC7389182 | biostudies-literature
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