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Electrical stimulation accelerate Wallerian degeneration and promote peripheral nerve regeneration.
Imaging resident and recruited macrophage contributions to Wallerian degeneration
To investigate the mechamism of electrical stimulation in the regulation of wallerian degeneration after peripheral nerve injury, we prepaired 3 samples for each group to ensure these data's quality. We then performed gene expression profiling analysis using data obtained from RNA-seq of each group.
ORGANISM(S): Rattus norvegicus 
2023-05-01 | GSE220261 | GEO
Wallerian degeneration (WD) involves the fragmentation of axonal segments disconnected from their cell bodies, segmentation of the myelin sheath, and removal of debris by Schwann cells and immune cells. The removal and downregulation of myelin-associated inhibitors of axonal regeneration and synthes...
ORGANISM(S): Mus musculus 
Local translation is engaged to sustain synaptic function in impaired Wallerian degeneration
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