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TranscriptomicsTranscription profiling of mouse Apoe knockouts treated with SRM2975 and C57Bl/6 mice treated with exhaust particles reveals Serum amyloid and serum amyloid P are not induced in response to diesel exhaust particles or carbon black
W evaluated an experimental particle exposure model, including markers of the acute phase system assessed as the hepatic mRNA expression of Sap, the murine homologue of CRP, and Saa1 and Saa3. Experiment Overall Design: 12-13 weeks old Apoe knockout mice (C57BL/6-Apoe tm1) mice were injected intrape...
ORGANISM(S): Mus musculus 
2009-05-02 | E-GEOD-11346 | biostudies-arrayexpress
TranscriptomicsEndogenous expression of an oncogenic PI3K mutation leads to activated PI3K pathway signaling and an invasive phenotype
The PTEN/PI3K pathway is commonly mutated in cancer and therefore represents a rational target for therapeutic intervention. In order to investigate the primary phenotype(s) mediated by mutant PIK3CA in a clean and highly patient-relevant context, we utilized a non-tumorigenic MCF10A parental and is...
ORGANISM(S): Homo sapiens 
2011-08-09 | E-GEOD-17785 | biostudies-arrayexpress
UnknownPirtobrutinib in relapsed or refractory B-cell malignancies (BRUIN): a phase 1/2 study.
Not available
S-EPMC11758240 | biostudies-literature
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