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TranscriptomicsMonocyte to macrophage differentiation and loading/deloading with lipoproteins (eLDL, oxLDL, HDL3)
Elutriated monocytes from 9 healthy donors with ApoE3/E3 genotype were differentiated for up to six days in vitro to macrophages using rhMCSF under serum-free conditions. Samples were taken on days 1, 4, 5 and 6 and analyzed for their transcriptomic profiles. After four days of differentiation cells...
ORGANISM(S): Homo sapiens 
2014-03-02 | E-MTAB-2298 | biostudies-arrayexpress
Genomicsena-DATASET-DEEP-08-06-2015-12:48:05:403-429 - samples
Human monocytes from a healthy male blood donor were obtained after written informed consent and anonymised. Library preparation was performed essentially as described in the “Whole‐genome Bisulfite Sequencing for Methylation Analysis (WGBS)” protocol as released by Illumina. The library was sequenc...
EGAD00001001390 | EGA
GenomicsEvolutionary origin and methylation status of human intronic CpG islands that are not present in mouse
Imprinting of the human RB1 gene is due to the presence of a differentially methylated CpG island (CGI) in intron 2, which is part of a retrogene derived from the PPP1R26 gene on chromosome 9. The murine Rb1 gene does not have this retrogene and is not imprinted. We have investigated whether the RB1...
EGAS00001000719 | EGA
GenomicsDEEP (Deutsches Epigenom Programm) DAC
Data Access Committee EGAC00001000179
EGAC00001000179 | EGA
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