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Transcriptomics1918 pandemic influenza virus and pneumococcus co-infection results in activation of coagulation and widespread pulmonary microvascular thrombosis in mice and humans
To study the effects of secondary bacterial infection during 1918 pandemic H1N1 influenza virus infection, BALB/c mice were inoculated with the fully reconstructed 1918 influenza virus followed by inoculation with pneumococcus 72h later. To study the effects of secondary bacterial infection during 1...
ORGANISM(S): Mus musculus 
2015-09-20 | E-GEOD-70445 | biostudies-arrayexpress
TranscriptomicsAn overlapping protein-coding region in Influenza A Virus Segment 3 modulates the host response
Segment 3 of influenza A virus contains a second open reading frame accessed via robosomal frameshifting. The frameshift product, PA-Z, comprises the endonuclease domain of viral PA protein with C-terminal demain encoded by the X-ORF and functions to repress cellular gene expression. PA-X also mo...
ORGANISM(S): Mus musculus 
2012-07-11 | E-GEOD-38112 | biostudies-arrayexpress
TranscriptomicsmicroRNA expression in human hepatitis c virus (HCV) liver biopsy samples
In order to infer the inverse expression relationships between microRNAs and mRNAs during HCV infection, we profiled both microRNA and mRNA expressions in HCV positive (HCV+) and HCV negative (HCV-) human liver biopsy tissue samples. This series includes all microRNA profiles. This series includes m...
ORGANISM(S): Homo sapiens 
2010-05-06 | E-GEOD-15288 | biostudies-arrayexpress
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