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TranscriptomicsCervical Tissue Long SAGE
16 Long SAGE libraries Keywords: Various degrees of cervical dysplasia Normal Cervical Tissue (N1, N2, N3, N4) CIN III, severe dysplasia cervical tissue (C1, C2, C3, C4, C5, C6) CIN I, mild dysplasia, cervical tissue (M1, M2, M3) CIN II, moderate dysplasia, cervical tissue (M4, M5, M6)
ORGANISM(S): Homo sapiens 
2008-02-18 | E-GEOD-7433 | biostudies-arrayexpress
TranscriptomicsThe long noncoding RNA expression profile of human intervertebral disc degeneration identified by microarray analysis
In addition to the well-known short noncoding RNAs as miRNAs, increasing evidence suggests that long noncoding RNAs (lncRNAs) act as key regulators in a wide aspect of biologic processes. Dysregulated expression of lncRNAs has been demonstrated being implicated in a variety of human diseases. Howeve...
ORGANISM(S): Homo sapiens 
2014-11-17 | E-GEOD-56081 | biostudies-arrayexpress
ProteomicsLC/MS Analysis of Phosphorylated Protein Changes in Mouse Brain Tissue After LPS Treatment and Angong Niuhuang Wan Administration
Introduction: Angong Niuhuang Wan (AGNHW), developed in the Qing dynasty (18th century) for treating consciousness disturbances caused by severe infections, has already been used to treat brain edema caused by ischemia-reperfusion. However, it remains unclear whether AGNHW can ameliorate vascular-or...
ORGANISM(S): Mus musculus (Mouse) 
2024-07-25 | PXD054069 | Pride
Lc/ms Agnhw Phosphoproteome 
TranscriptomicsLong noncoding RNA as modular scaffold of histone modification complexes
This SuperSeries is composed of the following subset Series: GSE22343: ChIP-chip of siGFP- or siHOTAIR-treated foreskin fibroblasts with anti-H3K4me2, anti-LSD1 or anti-SUZ12 antibodies on HOX tiling array GSE22344: ChIP-chip of siGFP- or siHOTAIR-treated foreskin fibroblasts with anti-LSD1 or anti...
ORGANISM(S): Homo sapiens 
2010-07-08 | E-GEOD-22345 | biostudies-arrayexpress
Transcriptomicslong noncoding RNAs expression data from GM0637 with and without DNA damage
GM0637 cell were treated with or without DNA damaging agent neocarzinostatin (NCS), and cells were harvested after 4 hours and 8 hours for the microarray analyses of whole-genome long noncoding RNAs. To examine how long noncoding RNAs are regulated in the DNA damage response, we assessed the genome-...
ORGANISM(S): Homo sapiens 
2013-01-17 | E-GEOD-43509 | biostudies-arrayexpress
TranscriptomicsA glimpse of natural selection of long-lived T cell clones in healthy life
We designed a lineage tracing method to label a wave of T cells produced in the thymus of young. TCR repertoire analysis revealed that the lineage-tracked CD4 memory-like T cells and T regulatory cells exhibited age-dependent enrichment of shared clonotypes, indicating that antigen matched T regulat...
ORGANISM(S): Mus musculus 
2016-07-21 | E-GEOD-84438 | biostudies-arrayexpress
UnknownZuogui Wan ameliorates high glucose-induced podocyte apoptosis and improves diabetic nephropathy in db/db mice.
Not available
S-EPMC9663993 | biostudies-literature
TranscriptomicsRNA-seq of Brassica napus seeds at different developmental stages
Understanding the regulation of lipid metabolism is vital for genetic engineering of Brassica napus (B. napus) to increase oil yield or modify oil composition. We report the application of Illumina Hiseq 2000 for transcriptome profiling of seeds of B. napus at different developmental stages, which m...
ORGANISM(S): Brassica napus 
2016-02-06 | E-GEOD-77637 | biostudies-arrayexpress
TranscriptomicsExpression profiling of cotton (Gossypium barbadense L. Pima S7) fiber transcriptome during the development
To gain novel insights into the molecular mechanisms underlying Pima cotton fiber quality, expression profiling of the Pima fiber transcriptome was performed as a function of development. The profiling was performed at 6 developmental time points: 8, 11, 14, 17, 21, and 24dpa. The expression profili...
ORGANISM(S): Gossypium barbadense 
2010-05-26 | E-GEOD-11689 | biostudies-arrayexpress
TranscriptomicsChIP-chip of siGFP- or siHOTAIR-treated foreskin fibroblasts with anti-LSD1 or anti-SUZ12 antibodies on human HG18 Nimblegen promoter arrays
Long intergenic noncoding RNAs (lincRNAs) regulate chromatin states and epigenetic inheritance. Here we show that the lincRNA HOTAIR serves as a scaffold for at least two distinct histone modification complexes. A 5’ domain of HOTAIR binds Polycomb Repressive Complex 2 (PRC2) while a 3’ domain of H...
ORGANISM(S): Homo sapiens 
2010-07-07 | E-GEOD-22344 | biostudies-arrayexpress
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